1.A.43.1.18
Fluoride transporter,CrcB of 122 aas and 4 TMSs (Baker et al. 2012). It is important for reducing fluoride concentrations in the cell, thus reducing its toxicity. Several of these fluoride exporter genes are regulated by fluoride-regulated riboswitches. M. extorquens has several F- exporters that are regulated by F--riboswithches because this organims can use halogenated hydrocarbons as carbon sources, and they release the toxic halogen ion into the cytoplasm. They need to pump it out to survive. (Baker et al. 2012)
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| Accession Number: | C7CD71 |
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| Protein Name: | Putative fluoride ion transporter CrcB |
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| Length: | 122 |
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| Molecular Weight: | 12468.00 |
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| Species: | Methylorubrum extorquens (strain DSM 6343 / CIP 106787 / DM4) [661410] |
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| Number of TMSs: | 4 |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MNTLLVFLGA GLGGVMRYGV NAWAVRLGAS FPWGTLGINV AGSVLMGIVT GWLAARGGPP
61: QARLFVATGI LGGFTTFSTF SLEAFTLMER GDGLAALAYV LVSVLAGIGG LALALIVMRH
121: AL