1.A.43.2.4
Plasma membrane fluoride ( > chloride) export channel of 375 aas and 8 TMSs, FEX1 (Li et al. 2013). The two homologous 4 TMS domains are functionally assymetric (Smith et al. 2015). There are two very similar fex genes in S. cerevisiae, the other having TC# 1.A.43.2.5. Fex1 is consitutively synthesized (Smith et al. 2015).
|
| Accession Number: | Q08913 |
|---|
| Protein Name: | UPF0695 membrane protein YOR390W |
|---|
| Length: | 375 |
|---|
| Molecular Weight: | 41985.00 |
|---|
| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
|---|
| Number of TMSs: | 8 |
|---|
| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
fluoride, chloride |
|---|
1: MIFNPVISNH KLSHYIHVFC TFTTFCILGT ETRQAITALS TYTPAFVTAP TVLWSNCSSC
61: MLMGIMQSLN AYTWMKDHQV LFLGVTTGYC GALSSFSSML LEMFEHSTNL TNGNIANHTK
121: LPNRAYGIME FLSVLLVHLM VSMGSLIFGR QLGKEVIVAY GSSSFSKPYT PPSDTVKENA
181: GDVDTQEMEK NILEFKFKTP APFFKKFFDI VDKLAYALAF PLIILFVVLC AYYENYSRGK
241: WTLPCLFGIF AGFLRYWLAE MFNKTNKKFP LGTFLANVFA TLLIGIFTMV QRGKKHFSTD
301: VPIVNSLNSC HIVSALISGF CGTLSTISTF INEGYKLSFI NMLIYYTVSI AISYCLLVIT
361: LGSYAWTRGL TNPIC