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|---|---|
| Accession Number: | Q9BSA4 |
| Protein Name: | Tweety homologue of Homo sapiens aka TTYH2 protein (Fragment) |
| Length: | 534 |
| Molecular Weight: | 58772.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 5 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | chloride |
Cross database links:
| RefSeq: | NP_116035.5 NP_443101.1 |
|---|---|
| Entrez Gene ID: | 94015 |
| Pfam: | PF04906 |
| OMIM: |
608855 gene |
| KEGG: | hsa:94015 |
Gene Ontology
GO:0034707
C:chloride channel complex
GO:0005886
C:plasma membrane
GO:0005254
F:chloride channel activity
GO:0005515
F:protein binding
GO:0006811
P:ion transport
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References (8)[1] “TTYH2, a human homologue of the Drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma.” Rae F.K.et.al. 11597145 [2] “DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.” Zody M.C.et.al. 16625196 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [5] “The full-ORF clone resource of the German cDNA consortium.” Bechtel S.et.al. 17974005 [6] “A novel human Cl(-) channel family related to Drosophila flightless locus.” Suzuki M.et.al. 15010458 [7] “Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.” Olsen J.V.et.al. 17081983 [8] “TTYH2, a human homologue of the Drosophila melanogaster gene tweety, is up-regulated in colon carcinoma and involved in cell proliferation and cell aggregation.” Toiyama Y.et.al. 17569141
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MQAARVDYIA PWWVVWLHSV PHVGLRLQPV NSTFSPGDES YQESLLFLGL VAAVCLGLNL 61: IFLVAYLVCA CHCRRDDAVQ TKQHHSCCIT WTAVVAGLIC CAAVGVGFYG NSETNDGAYQ 121: LMYSLDDANH TFSGIDALVS GTTQKMKVDL EQHLARLSEI FAARGDYLQT LKFIQQMAGS 181: VVVQLSGLPV WREVTMELTK LSDQTGYVEY YRWLSYLLLF ILDLVICLIA CLGLAKRSKC 241: LLASMLCCGA LSLLLSWASL AADGSAAVAT SDFCVAPDTF ILNVTEGQIS TEVTRYYLYC 301: SQSGSSPFQQ TLTTFQRALT TMQIQVAGLL QFAVPLFSTA EEDLLAIQLL LNSSESSLHQ 361: LTAMVDCRGL HKDYLDALAG ICYDGLQGLL YLGLFSFLAA LAFSTMICAG PRAWKHFTTR 421: NRDYDDIDDD DPFNPQAWRM AAHSPPRGQL HSFCSYSSGL GSQTSLQPPA QTISNAPVSE 481: YMNQAMLFGR NPRYENVPLI GRASPPPTYS PSMRATYLSV ADEHLRHYGN QFPA