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1.A.54.2.1 Archaeal presenilin homologue (DUF1119; COG3389; PSN). Members of the peptidase A22B superfamily (found in many archaea, but not bacteria, shows some sequence similarity to members of the LIV-E family, e.g., 2.A.78.2.1))
Accession Number:	Q18K19
Protein Name:	PSN aka HQ1505A
Length:	339
Molecular Weight:	35728.00
Species:	Haloquadratum walsbyi (strain DSM 16790) [362976]
Number of TMSs:	9
Location¹ / Topology² / Orientation³:	Endoplasmic reticulum membrane¹ / Multi-pass membrane protein²
Substrate	calcium(2+)

RefSeq:	YP_657277.1
Entrez Gene ID:	4192339
Pfam:	PF06550
BioCyc:	HWAL362976:HQ1505A-MONOMER
KEGG:	hwa:HQ1505A
Gene Ontology GO:0016021 C:integral to membrane
References (1) [1] “The genome of the square archaeon Haloquadratum walsbyi: life at the limits of water activity.” Bolhuis H.et.al. 16820047

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MHRRVAFGIG FTAVLFFLIQ LGALALVPTF YEQGYQTVED PTNPTNSLLY IGAILVATAV 
61:	MLAAFKYELQ WLVKGFITLA AGSLAWYVFS VFFSPLLAAI PAVGLAVLLI IYPEWYIIDA 
121:	AGVLMGAGAA GLFGISFGLL PALVLLSILA VYDAISVYGT EHMLDLAAGV MDLNLPVILV 
181:	IPTTLSYSLR EDVSPVATDD NTNVSVSDNE THTHANELAE HDAETPSSID ETSTDDSHIR 
241:	DAFFIGLGDA VMPTVLVASA AFFLPGELTP SLGIFGIPAM TLPALTAMIG TFIGLFVLMW 
301:	LVVKGRAHAG LPLLNGGAIG GYLIGALLSG VPLIRALGL

1.A.54.2.1
Archaeal presenilin homologue (DUF1119; COG3389; PSN). Members of the peptidase A22B superfamily (found in many archaea, but not bacteria, shows some sequence similarity to members of the LIV-E family, e.g., 2.A.78.2.1))

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

1.A.54.2.1Archaeal presenilin homologue (DUF1119; COG3389; PSN). Members of the peptidase A22B superfamily (found in many archaea, but not bacteria, shows some sequence similarity to members of the LIV-E family, e.g., 2.A.78.2.1))

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

1.A.54.2.1
Archaeal presenilin homologue (DUF1119; COG3389; PSN). Members of the peptidase A22B superfamily (found in many archaea, but not bacteria, shows some sequence similarity to members of the LIV-E family, e.g., 2.A.78.2.1))