1.A.54.3.5 Impas 1 (IMP1, HM13, PSL3, APP, MARP086) possesses endoproteolytic activity against multipass membrane protein substrates, cleaving the presenilin 1 holoprotein (Moliaka et al. 2004).
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Accession Number: | Q8TCT9 |
Protein Name: | Minor histocompatibility antigen H13 |
Length: | 377 |
Molecular Weight: | 41488.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 8 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
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1: MDSALSDPHN GSAEAGGPTN STTRPPSTPE GIALAYGSLL LMALLPIFFG ALRSVRCARG
61: KNASDMPETI TSRDAARFPI IASCTLLGLY LFFKIFSQEY INLLLSMYFF VLGILALSHT
121: ISPFMNKFFP ASFPNRQYQL LFTQGSGENK EEIINYEFDT KDLVCLGLSS IVGVWYLLRK
181: HWIANNLFGL AFSLNGVELL HLNNVSTGCI LLGGLFIYDV FWVFGTNVMV TVAKSFEAPI
241: KLVFPQDLLE KGLEANNFAM LGLGDVVIPG IFIALLLRFD ISLKKNTHTY FYTSFAAYIF
301: GLGLTIFIMH IFKHAQPALL YLVPACIGFP VLVALAKGEV TEMFSYEESN PKDPAAVTES
361: KEGTEASASK GLEKKEK