TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.A.63.1.1









The α-helical pore-forming outer membrane nanomeric porin, Imp1227 or Ihomp1, of 85 aas and one TMS. The membrane protein Imp1227 is the main protein constituent of the unique outer sheath of the hyperthermophilic, chemolithoautotrophic archaeum Ignicoccus hospitalis. With its molecular mass of only 6.23 kDa, Imp1227 is found to be incorporated into the outer membrane to form large, stable complexes. When separated by SDS-PAGE, they exhibit apparent masses of about 150, 50, 45 and 35 kDa.  Electron micrographs of negatively stained samples confirmed that isolated membranes are tightly packed with round complexes, about 7 nm in diameter, with a central, stain-filled 2 nm pore; a local two-dimensional crystalline arrangement in the form of small patches can be seen by tomographic reconstruction. Using secondary structure predictions and molecular modelling, an alpha-helical transmembrane domain is proposed; for the oligomer, a ring-shaped nonamer with a central 2 nm pore was a likely arrangement.

Archaea
Crenarchaeota
Imp1227 of Ignicoccus hospitalis (A8ABZ0)
1.A.63.1.2









Uncharacterized protein of 78 aas and 1 N-terminal TMS.

Archaea
TACK group
UP of Crenarchaeota archaeon
1.A.63.2.1









Transmembrane DUF4845 protein with 120 aas and one TMS.

Bacteria
Proteobacteria
Transmembrane protein of Acidovorax sp. KKS102
1.A.63.2.2









Uncharacterized protein of 129 aas and 1 TMS

Bacteria
Proteobacteria
UP of Congregibacter litoralis
1.A.63.2.3









Uncharacterized protein of 130 aas and 1 TMS/

Bacteria
Proteobacteria
UP of Legionella pneumophila
1.A.63.2.4









Uncharacterized DUF4845 domain-containing protein of 192 aas and 1 N-terminal TMS.

Bacteria
Proteobacteria
UP of Thiobacillus sp.
1.A.63.2.5









Uncharacterized DUF4845 domain-containing protein of 131 aas and 1 N-terminal TMS.

Bacteria
Proteobacteria
UP of Cupriavidus sp.
1.A.63.2.6









Uncharacterized DUF4845 domain-containing protein of 92 aas and possibly two TMSs, N- and C-terminal.

Bacteria
Proteobacteria
UP of Betaproteobacteria bacterium
1.A.63.2.7









Uncharacterized DUF4845 domain-containing protein of 122 aas and 2 TMSs, one N-terminal and possibly a second, near the C-terminus of the protein.

Archaea
Euryarchaeota
UP of Halobacteria archaeon