1.A.69.3.5 High energy light unresponsive protein 1, Lite1; chemoreceptor GUR-2 of 439 aas and 8 TMSs. It is a photoreceptor for short wavelength (UV) light that mediates UV-light-induced avoidance behavior (Edwards et al. 2008, Liu et al. 2010, Gong et al. 2016). It directly senses and absorbs both UV-A and UV-B light with very high efficiency (Gong et al. 2016). Absorption of UV-B but not UV-A light shows resistance to photobleaching.
In contrast to other photoreceptors, it does not use a prosthetic
chromophore to capture photons and only depends on its protein
conformation. It may play a role in response to white light exposure (De Magalhaes Filho et al. 2018) as well as color detection (Ghosh et al. 2021).
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Accession Number: | Q17990 |
Protein Name: | High-energy light unresponsive protein 1 |
Length: | 439 |
Molecular Weight: | 50554.00 |
Species: | Caenorhabditis elegans [6239] |
Number of TMSs: | 8 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
cation |
---|
1: MPPPSSHSNI FHSTFKHTVK ETMANAKKTM IAKILSSRNK WAICDRTLYP IYYLLLILGL
61: NQSIRPNNSL LFRIYSWLVF CLLLFTTLRK FNQVGVRPNG TRENLQEFFA NPRSMITLCN
121: ALIMLSGLLA SLQLYTLGAK RLKPLKILCQ FSLNVRTKQA ERRQFMINTF LAVFSGLLAL
181: TMAATYAMSK WGYILYIVGT PNLDTETIFC VLLDSYALFV SRAAISALAI LFYQHCSVIR
241: RSIKHLINEM VPAEQDECPL PESSLQKIHD CQISYQRIFN GKAVIEEYYS FVLFYSYGVC
301: IPIFCFLMFV GMSAQSICWS EVVSIVIWIV NAILVLLLFS LPAFMINEDG DRLVASSFRM
361: YHETFHEERD LTVLSQMTFF TFQIHSTKLT LSACNYFYMD RSILLSLFSA ILTYFLILWE
421: FDIKNNQSLQ NIANHTIHT