1.A.69.3.8 Gustatory receptor family protein 3, Gur-3, of 447 aas and 8 - 9 TMSs. It is a chemoreceptor involved in light-induced avoidance behavior (Bhatla and Horvitz 2015) and probably acts as a molecular sensor in I2 pharyngeal neurons, required
for the inhibition of feeding in response to light and hydrogen peroxide. It may be involved in circadian rhythms, probably by acting as a light sensor (Goya et al. 2016). Although it acts with Lite-1 in color detection, it does not act as a photoreceptor (Ghosh et al. 2021).
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Accession Number: | O18280 |
Protein Name: | Gustatory receptor family protein 3 |
Length: | 447 |
Molecular Weight: | 51228.00 |
Species: | Caenorhabditis elegans [6239] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
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1: MTITASNTLE FKWTSPRSSR SSFRTTTDAE QKISIDMSNT YCDQVLGPLY SYMMVLGLNH
61: THSSARNTMF KWPLTIYNYL TLAILTAATI RRISQIKQKS ATNEEKDAAF HVLNPTFVLT
121: LCHALLMFSG LAAGFLLLKL QKQREKMYHV LDQGLGRNRN EEHDSHHFKL NKLFISISFS
181: FAAALSFVQI ATKMRYLDLP DTPDLINRKI YFVILEGYVI FIASSCISLV AILFFQLCRI
241: LQFSIGQLIE EMVPKEKEEC PLPEQSLQQI HDVQIHYQEI SNAKLYIEQN FSFSLFYTYG
301: CCIPLTCLLG YIAFRNGIQA DMAETFSVAI WLTNTMLALM LFSIPAFMIA EEGDKLLTAS
361: FKMYHETLCE ERDLLVLSQM SFLSFQMHAT KLTLTAGNFF MMNRKIMISL FSAIFTYFLI
421: LVQFDAEKER AGECNNQSRV LIVQPPV