| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
1.A.74.1.1 | Mitsugumin 23 (MG23), also called TM protein 109 (Venturi et al., 2011). MG23 is a Ca2+ channel protein that is regulated by cytoplasmic Zn2+, and dysregulation of this ion channel plays a role in diastolic sarcoplasmic reticulum Ca2+ homeostasis, promoting leakage from the SR (Reilly-O'Donnell et al. 2017). | Eukaryota |
Metazoa, Chordata | MG23 of Mus musculus (Q3UBX0) |
|
1.A.74.1.2 | Mitsugumin23 (TMEM109) of 243 aas and 5 TMSs (Takeshima et al. 2015). | Eukaryota |
Metazoa, Chordata | Mitsugumin23 of Homo sapiens |
|
1.A.74.2.1 | Bri3 binding protein, isoform CRA_a | Eukaryota |
Metazoa, Chordata | Bri3 of Mus musculus (Q8BXV2) |
|
1.A.74.2.2 | BRI3 binding protein. Plays a role in tumorigenesis. BRI3 is a member of the BRI gene family that includes the familial British and Danish dementia gene BRI2. BRI3 interacts with the Amyloid Precursor Protein, APP, and serves as an endogenous negative regulator of Abeta production (Matsuda et al. 2009). | Eukaryota |
Metazoa, Chordata | BRI3 BP of Homo sapiens |
|
1.A.74.3.1 | Uncharacterized protein of 234 aas and 5 TMSs | Eukaryota |
Metazoa, Chordata | UP of Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) |