1.A.75.1.25
Piezo-type mechanosensitive ion channel homolog isoform X1 of 2572 aas and ~38 TMSs with nine 2 + 1 + 1 TMS repeat units followed by 2 C-terminal TMSs that comprise the channel. It modulates vacuole morphology during tip growth (Radin et al. 2021).
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| Accession Number: | XP_024369685 |
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| Protein Name: | XP_024369685.1 piezo-type mechanosensitive ion channel homolog isoform X1 [Physcomitrium patens] |
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| Length: | 2573 |
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| Molecular Weight: | |
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| Species: | Physcomitrium patens [3218] |
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| Number of TMSs: | 40 |
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| Substrate |
cation |
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1: MQASAIGAFA PVVLLCAALG SWSLISSCFL ISFFVVQFKI QRRGLTRPRS GLWMSVVLLA
61: TIVIVVEGLV AIGCTVFGAE GSFLDSQWLK VLGLASLNPW ESSSEVFLIM APQFAVALTA
121: ACALYHEQHS TMSGSAHAYY DEDTFHWRAN LISFVLPTVQ LIAGVARPSW IALPYFIYSC
181: AGLLHWSMTS NFVGLARGWR PLMYCTGMHI MLQYLYQLPI SFPQELQDAA EYIGLFKCSM
241: LEMGWPEAVQ SLALIAFFML LCVAVNDLDE DRRQQLAESR DTLPTTYSRS ARSFTYGGSE
301: SDLLTESLLH SDQGSSHRNQ GPGHRESLNS RRWVIEQRRI LACQHATINF FTYGFPICMV
361: ALIGWSFVYA SLCAFALLLY VGYIFFAFPA ASTLQRLNPV LLGFILLYAL TTYFFNAAFS
421: IMKAKFDLGT EIWHLIGLWH YSTPGLFIFA QYALGLLLAT DIFVSNNILH NLGDPESPNG
481: EDANGLLEEG RQDIKLMVLA VVAWFVRRSA HVISLILIFN VGMKGGLLHA VYMGFFLSYL
541: LSSTVAKASR QSLILLCEVH FAILYLLRLD WISTHLADNA GMLKPFLSLL GVWHKSNFEE
601: FLSIAVLLVF SSVQNHGLKV ASSLSATVQQ SPQPPLGWGI FKTGNGRSIL LSVYASSNFN
661: HLQEESDASA HWITRFLATT AEKVRHTYHM FSTYIAYGTV LLVVYSVDQN YVAFGYLCLL
721: LFWIAGRQVV GRTEKRLWFP LLMYSAAVFV VRYTLSAFPI LHHYVDVRVS LRLYLGFDPA
781: ASLFQHLWDP LVILIVMEIF SFERSQKFFA PEDAEEGAYE VDSNLGLVAF VKRLLILHTG
841: KLLSVAVFYA ALTPVSALGF LYLVMLVVTC NMSKTSSLPG RTYVLYTSFI IIVEYLYQMW
901: GQDAEMFPDQ AHGEFTYWLG LRVFETGFWG LELGLRSRVI VLMMCILKCT TLGWHELLPA
961: SLRVDEHYGE PCLLFLPQGR RVGSSVRHSG LTEPLLEKTQ KRVTASEKQS VVSGQSFHST
1021: STSESDSSSS SVVRPKLSVP INSGTESGGR PNLESPWGSL SENRKWTRRG MLLLRQERYE
1081: AQLRTLGIIF KHRIEHFCQL YGLELSMLAL LLSSFALLNV FSLFYIFILA LCILLPRRTL
1141: KILWPFFVVL FACVMVTEYA VLGGSPPPWR VSSLHAPEPH LQCVQCWSSY TSHNFFCWQC
1201: WLGLTIDDRQ MLVAHFVVFI VSCFQLHANM AAGMLDPRSL HAVILPASDR LAWKEISYET
1261: TAQWTWLDYL RFAFYRHLLH VVLVLVFITG TLQYDVLHLG YLAMSLIFFR MRGTIMERRN
1321: SIFRFLRLYN FILIVASLTY QAPYFGFAGV QTCTLPQGLL SYIGLYKYDH GFRITERSAL
1381: VDITIFCVVG LQAHIFRSRE FEQVLRYLEA QQVEARAHAQ EDKAEWKKEQ LQRIREMEER
1441: KHHRRVQVDK MKHDMLHMQL RLEVLDSSGP QFELADRKKS IQPSASPYSQ SPRPLVDTPR
1501: VLERIASETA ATRGPDAGTE RRLSFEKDPT RVGYVDRESD ESDAEVKGVR RRKPVIKKKS
1561: RSSEDALATE RQEKLLGSQP GDHRKTGSDV SFEGKHQSRP VLMSGVQLLE EGVAQVQNLG
1621: NKALANLVGL LNLENEDDST EGSSTEEEAH VPAEKEEITI QELVDNSKVP PKVSVDEMSH
1681: QQSQYMNETW RRLFMIFSFI YSQLRANTDL VCYVFFILVY VWNFSFLTLM FPAVLFLYAL
1741: LVNPGPSQYF WLAMLIYIEF NILLQYCYQI HQQHCSDQYI PPWLKKFGIP GGEMTHSFVL
1801: SVLPLFLVYL ATLVQSSIKA RDGEWMLVTE SSPFTSSRRL LDQENQAGPP SRLTMSQRMR
1861: ALVAQISGWF TSLRLGMLRY FQALTNGSEA PPHFVQVSLD VGKWPEAGIQ PETIESGFNR
1921: LLASVRQPRL PSSDDSSMNH SSRVRVESIE SSPDRPQVAL AVLEVIYVAS PQTFLADSHH
1981: ISLTPARDLA DELLRAKEEN LLEETRFPYP ILSVIPGGKR EVDLYAYIFG TELLTFVFVA
2041: LFYQPLMKHS SGLFDVTQVE DQFPKGFIIV LMTLFFLIVV DRVLYLCSFA SGKVIYYLCT
2101: LMLYTGYVSQ FVWSIEDHET VEAKNKHEFR LLPLRIFYMM KALSLALQAF QIKYGLPHKS
2161: ALYGQFLARK VNLMSWNCFR LYRALPFLFE LRCVLDWSCT TTALNMYDWL KLEDIYGSLF
2221: LVQCDNKLNR EKHRLGEKQS MFIKFCSGVL LFAILIAVIW APMLIYSSGN PTNTPNLVMD
2281: VHAGIAVKTA GGVFKLYETG LCHNHTLTGT RYPDEHRSVL AGYDPRDVQV ICCEPDGASL
2341: WLIPPSTLKS LIHSIDSDDL VFSSWWDFHR ERPKEKELAS YALQPQQDKN VLPDQLKAVL
2401: NGTSNSIYID KLYPQYFRVP SSGDVHILEG SNVYISGNLT LKREFGQAWW SFESDISLAN
2461: DCGSMMGPAA ITVSEEVPPK GLLGETLSRF SIWSLYITFV LAVGRFIRLQ CADIRMRIPY
2521: ENFPACDRLV AICEDIYAAR AAGELELEEG LFWTLIKIYR APYILMEYTK VE