| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
1.A.76.1.1 | Magnesium transporter, MagT1; Ost3_Ost6; SLC58A1 (Goytain and Quamme, 2005; Schmitz et al., 2007; Zhou and Clapham, 2009; Gyimesi and Hediger 2022). As of 2018, the function of this protein as a Mg2+ transporter was under debate (Schäffers et al. 2018). This protein is of 335 aas with 5 TMSs in a 1 (N-terminal) + 2 + 2 (C-terninal) TMS arrangement. | Eukaryota |
Metazoa, Chordata | MagT1 of Homo sapiens (Q9H0U3) |
|
1.A.76.1.2 | Mg2+ transporter; also called Tumor suppressor candidate 3 isoform a, Tusc3a (69% identity with MagT1) (Zhou and Clapham, 2009). It can transport Mg2+, Fe2+, Cu2+ and MnFe (Gyimesi and Hediger 2022). | Eukaryota |
Metazoa, Chordata | Tusc3a of Homo sapiens (Q13454) |
|
1.A.76.1.3 | Magnesium transporter protein 1 (MagT1) with a thioredoxin domain (residues 50 - 150) and an Ost3/Ost6 domain (residues 160 - 310 with 4 TMSs). | Eukaryota |
Metazoa, Chordata | MagT1 of Danio rerio |
|
1.A.76.1.4 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 | Eukaryota |
Evosea | Ost3 of Dictyostelium discoideum |
|
1.A.76.1.5 | Ubiquitin conjugating enzyme of 345 aas with 4 C-terminal TMSs | Eukaryota |
Ciliophora | Ubiquitin conjugating enzyme of Oxytricha trifallax |
|
1.A.76.1.7 | Putative magnesium transport protein of 354 aas and 4 C-terminal TMSs. | Eukaryota |
Ciliophora | MagT1 homologue of Albugo laibachii |
|
1.A.76.1.8 | Glycosyl transferase, Ost3 of 350 aas and 4 TMSs. This protein is a subunit of the yeast oligosaccharyltransferase complex involved in N-glycosylation (Wild et al. 2018). It is not the catalytic subunit (see TC# 9.B.142.3.14). | Eukaryota |
Fungi, Ascomycota | Ost3 of Saccharomyces cerevisiae |
|
1.A.76.1.9 | Ost6-like protein of 332 aas and 4 TMSs. | Eukaryota |
Fungi, Ascomycota | Ost6 of Saccharomyces cerevisiae (Baker's yeast) |
|
1.A.76.1.10 | Ost3/Ost6 homologue of 334 aas and 5 TMSs | Eukaryota |
Viridiplantae, Chlorophyta | Ost3-like protein of Chlamydomonas reinhardtii (Chlamydomonas smithii) |
|
1.A.76.1.11 | Uncharacterized protein of 277 aas | Eukaryota |
Foraminifera | UP of Reticulomyxa filosa |
|
1.A.76.1.12 | Uncharacterized protein of 362 aas | Eukaryota |
Heterolobosea | UP of Naegleria gruberi (Amoeba) |
|
1.A.76.1.13 | Uncharacterized protein of 328 aas and 7 (or 5) TMSs | Eukaryota |
Fungi, Ascomycota | UP of Tetrapisispora blattae (Yeast) (Kluyveromyces blattae) |
|
1.A.76.1.14 | Mg2+ transporter, MagT1 homologue of 331 aas | Eukaryota |
Fungi, Ascomycota | MagT1 homologue of Pyronema omphalodes |
|
1.A.76.2.1 | Oligosaccharyltransferase complex/magnesium transporter family protein of 173 aas and 3 or 4 TMSs. The proteins in this family are part of a complex of eight ER proteins that transfers core oligosaccharide from dolichol carrier to Asn-X-Ser/Thr motifs. This family includes both OST3 and OST6, each of which contains four predicted transmembrane helices. Disruption of OST3 and OST6 leads to a defect in the assembly of the complex. Hence, the function of these genes seems to be essential for recruiting a fully active complex necessary for efficient N-glycosylation. | Eukaryota |
Viridiplantae, Streptophyta | Uncharacterized protein of Arabidopsis thaliana (Mouse-ear cress) |
|
1.A.76.2.2 | Uncharacterized protein of 148 aas and 3 TMSs | Eukaryota |
Fornicata | UP of Giardia intestinalis (Giardia lamblia) |
|
1.A.76.2.3 | Uncharacterized protein of 159 aas and 3 TMSs | Eukaryota |
Rhodophyta | UP of Cyanidioschyzon merolae |
|
1.A.76.2.4 | Uncharacterized protein of 433 aas with 3 N-terminal TMSs. | Eukaryota |
Evosea | UP of Dictyostelium discoideum (Slime mold) |
|
1.A.76.2.5 | Oligosaccharyl transferase complex subunit, EgrG of 144 aas and 3 TMSs. | Eukaryota |
Metazoa, Platyhelminthes | OST3 family member of Echinococcus granulosus (Hydatid tapeworm) |
|
1.A.76.2.6 | OST3/OST6 superfamily protein of 158 aas and 3 TMSs. | Eukaryota |
Parabasalia | OST3 family protein of 158 aas |
|
1.A.76.2.7 | OST3/OST6 Family protein of 159 aas and 3 TMSs. | Eukaryota |
Parabasalia | OST3 homologue of Trichomonas vaginalis |
|
1.A.76.2.8 | Oligosaccharidyl transferase DS2 of 173 aas and 4 TMSs | Eukaryota |
Metazoa, Nematoda | DS2 of Loa loa (Eye worm) (Filaria loa) |
|
1.A.76.2.9 | Oligosaccharidyl transferase, OstC of 149 aas and 3 TMSs in a 1 + 2 TMS arrangement. It may be involved in sperm membrane integrity (Illa et al. 2021). OSTA and OSTC are useful self-assessment tools for osteoporosis detection (Bui et al. 2022). | Eukaryota |
Metazoa, Chordata | OstC of Homo sapiens |
|
1.A.76.2.10 | OstCL of 119 aas and 3 TMSs in a 1 + 2 TMS arrangement. | Eukaryota |
Metazoa, Chordata | OstCL of Homo sapiens |