1.A.77.1.4 Slime mold MCU homologue of 275 aas and 2 TMSs. The structure of the N-terminal domain (NTD) has been solved at 1.7 A resolution (Yuan et al. 2020). The oligomeric DdMCU-NTD contains four helices and two strands arranged in a fold that is completely different from the known structures of other MCU-NTD homologues. This domain may regulate channel activity (Yuan et al. 2020).
|
Accession Number: | Q54LT0 |
Protein Name: | Putative uncharacterized protein |
Length: | 275 |
Molecular Weight: | 31756.00 |
Species: | Dictyostelium discoideum (Slime mold) [44689] |
Number of TMSs: | 2 |
Substrate |
calcium(2+), magnesium(2+) |
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1: MNSFVIRNGF GLVRTFNTRL FTTSTQNLEG ELKTILGQAK VSKLQEKLKL DPRSKITFND
61: FKGIAKEVGI EEKEINSVSN ALAQSGSIIY LPNSLNENLK TSVFTKPAHI YQSLEHILDI
121: ENKGVGLNKL IESKKSEINS LRQKIQPLEE KKQVIDRKAH RRATAIIWTG LGYCFAQAAI
181: LARLTWWDLS WDIIEPVSYF LTFGSVLIGY TYFTMTKTEF TYEALNHRLF SKRQDKLFKR
241: NNFPKEDYEN LVQAIDKKEK ELKELELATK YDHTH