TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.8.11.5
Probable aquaporin PIP2-6 (Plasma membrane intrinsic protein 2-6) (AtPIP2;6) (Plasma membrane intrinsic protein 2e) (PIP2e). In the radish (Raphaus sativus), there are 61 genes encoding aquaporins, and RsPIP2-6 is induced with high NaCl, and is involved in the salt stress response (Yi et al. 2022).  The plasma membrane intrinsic protein OsPIP2;6 is involved in root-to-shoot arsenic translocation in rice (Oryza sativa L.) (Meselhy et al. 2024).

Accession Number:Q9ZV07
Protein Name:Probable aquaporin PIP2-6
Length:289
Molecular Weight:31050.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate water

Cross database links:

Entrez Gene ID: 818487   
Pfam: PF00230   
KEGG: ath:AT2G39010   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0009624 P:response to nematode
GO:0055085 P:transmembrane transport
GO:0006833 P:water transport

References (5)

[1] “Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.”  Lin X.et.al.   10617197
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “From genome to function: the Arabidopsis aquaporins.”  Quigley F.et.al.   11806824
[4] “Temporal analysis of sucrose-induced phosphorylation changes in plasma membrane proteins of Arabidopsis.”  Niittylae T.et.al.   17586839
[5] “Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.”  Reiland S.et.al.   19376835

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MTKDELTEEE SLSGKDYLDP PPVKTFEVRE LKKWSFYRAV IAEFIATLLF LYVTVLTVIG 
61:	FKSQTDINAG GGACASVGLL GISWAFGGMI FILVYCTAGI SGGHINPAVT FGLFLASKVS 
121:	LVRAVSYMVA QCLGATCGVG LVKVFQSTYY NRYGGGANML SDGYNVGVGV GAEIIGTFVL 
181:	VYTVFSATDP KRNARDSHIP VLAPLPIGFS VFMVHLATIP ITGTGINPAR SFGAAVIYNN 
241:	QKAWDDQWIF WVGPFVGAAI AAFYHQFVLR AGAMKAYGSV RSQLHELHA