1.A.8.8.17
Aquaporin-3, Aqp-3 of 271 aas. Transports water, glycerol, hydrogen peroxide and urea (Geadkaew et al. 2015). AQP3 induces the production of
chemokines such as CCL24 and CCL22 through regulating the amount of cellular H2O2 in M2 polarized
alveolar macrophages, implying a role of AQP3 in asthma (Ikezoe et al. 2016).
|
| Accession Number: | AIZ03631 |
|---|
| Protein Name: | AIZ03631.1 aquaporin 3 [Opisthorchis viverrini] |
|---|
| Length: | 272 |
|---|
| Molecular Weight: | |
|---|
| Species: | Opisthorchis viverrini [6198] |
|---|
| Number of TMSs: | 6 |
|---|
| Substrate |
hydrogen peroxide, water, urea, glycerol |
|---|
1: MPVKGVFVSE SSETTLSRLF RTTRCFLAEF LGTALICYVS VIYQHGPVPA AFVVGLTLAW
61: IAWVFGPVSG AHVNPVVSLM MLLVRKVWFL DALIYIVAQL LGSMAGSWIG TLAVPAVDAG
121: NTLGMTTISA NITVGQAIGL EIVATALLLL VILSAVDELR PKPWNVGNVT IFPFIFGATL
181: ALLASLLGDL TGASMNPARS FGPAVVNNNF TDLWVYIVGP FIGALLATVL YEFLLTEGAC
241: CNRVKAWFTE ADYDRARDYR VPDGNSLNLV N