1.A.8.8.28
Aquaporin-2, Aqp2, of 275 aas and 6 TMSs.It is subject to hyperosmotic stimulation in Chick Kidney (Sugiura et al. 2008). It is highly similar to the quail (Coturnix coturnix) ortholog which has been studied and shown to be a mercury-inhibited, vasotocin-sensitive water channel in the kidney (Yang et al. 2004).
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| Accession Number: | NP_001279001.1 |
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| Protein Name: | NP_001279001.1 aquaporin-2 [Gallus gallus] |
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| Length: | 276 |
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| Molecular Weight: | |
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| Species: | Gallus gallus [9031] |
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| Number of TMSs: | 6 |
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| Substrate |
water |
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1: MMWELRSVAF TRAVLAEFLA TLVFILFGLG SALNWPSASA PSILQIALAF GLAIGTLVQA
61: LGHISGAHIN PAVTVACLIG SHVSFLRAVF YVVAQLLGAV AGAAILHEIT PADSREGLAI
121: NKLHNETTTG QAVTVELFLT FRLVLCIFAS TDERREDNMG SPALSIGLSV AVGHLLGIRY
181: TGCSMNPARS FAPAVIVGDF SDHWVFWVGP LVGAAAASII YNYVLFPQSK TFSERLAIFK
241: GMEPEEDWAE REARRRQSVE LHSPQSLPRG ISEKV