1.A.8.9.10 Aqp9 or Aqp-h9 of 294 aas. Takes up glycerol as well as water, and thereby contributes to freeze tolerance (Hirota et al. 2015). An almost identical orthologue, HC-9 in Dryophytes chrysoscelis (gray treefrog), similarly facilitates glycerol permeability. Both the transcriptional and translational levels of HC-9 change in response to thermal challenges, with a unique increase in liver during freezing and thawing (Stogsdill et al. 2017).
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Accession Number: | BAR45953 |
Protein Name: | BAR45953.1 aquaporin-9 [Dryophytes japonicus] |
Length: | 295 |
Molecular Weight: | |
Species: | Dryophytes japonicus [109175] |
Number of TMSs: | 6 |
Substrate |
water, glycerol |
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1: MRERRSCLEK LALRNSLARE TLSEFFGTCL LVTFTCCSIA TAVLNYGSSG GTLGATVGCS
61: LAVTMAIYAS GGVSGGHVNP AVSFAMSMTG KLPWVKLPFY ITAQFLGAIT GSAAVFGVYY
121: DALMAYSGGV FRVTGPNATA QIFATYPSPY LSTLNGLVDQ MMSTALLLML IFAIFDKKNM
181: PAPKGLEPVA VGLLILTLAL SLGSNCGAAM NPARDLGPRI FTALAGWGPE VFTAGGSFWW
241: IPVVGPMLGA VIGSYIYILC IDIHHKKEPD HEMDPDHFEK HELANMTEKP KTRC