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1.B.163.  The Cell Wall (Outer Membrane) Porin-2 (PorA2) Family

This family (DUF3068; pfam11271) includes members of about 375 aas with two very hydrophobic TMSs at the N- and C-termini.  The PorA of Corynebacterium amycolatum forms water-filled channels that favor the permeation of cations (Dörner et al. 2009, Soltan Mohammadi et al. 2013). The cell-wall channel is wide and water-filled and has a narrow selectivity for cations (Dörner et al. 2009).

References associated with 1.B.163 family:

Dörner, U., B. Schiffler, M.A. Lanéelle, M. Daffé, and R. Benz. (2009). Identification of a cell-wall channel in the corynemycolic acid-free Gram-positive bacterium Corynebacterium amycolatum. Int Microbiol 12: 29-38. 19440981
Piselli, C., L. Benier, C. Koy, M.O. Glocker, and R. Benz. (2022). Cell wall channels of Rhodococcus species: identification and characterization of the cell wall channels of Rhodococcus corynebacteroides and Rhodococcus ruber. Eur Biophys. J. [Epub: Ahead of Print] 35567623
Soltan Mohammadi, N., S. Mafakheri, N. Abdali, I. Bárcena-Uribarri, A. Tauch, and R. Benz. (2013). Identification and characterization of the channel-forming protein in the cell wall of Corynebacterium amycolatum. Biochim. Biophys. Acta. 1828: 2574-2582. 23811360