TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.B.164.1.1









The nutrient outer membrane channel, CpnT, of 846 aas and 1 N=terminal TMS and possibly two more TMSs at about residues 220 and 270.  It can be mutated to serve as a Ca2+ channel and promote cell death (D'Elia and Weinrauch 2023).

Bacteria
Actinomycetota
CpnT of Mycobacterium tuberculosis
1.B.164.1.2









Uncharacterized protein of 426 aas with two putative TMSs, one N-terminal and one at residues 250.  Only the first domain, the outer membrane channel domain, presumably specific for nutrients, is present, not the toxin domain which is the C-terminal domain of CpnT (TC#1.B.164.1.1).

Bacteria
Actinomycetota
UP of Nocardia araoensis
1.B.164.1.3









Uncharacterized protein of 475 aas and 2 or possibly 3 TMSs, one at the N-terminus, one at about residue 220, and possibly a third (with less hydrophobicity) at about residue 270.

Bacteria
Actinomycetota
UP of Gordonia rubripertincta
1.B.164.1.4









Uncharacterized protein of 475 aas and 2 or 3 TMSs, one at the N-terminus of the protein and one or two are residues 320 - 370.

Bacteria
Actinomycetota
UP of Streptomyces tanashiensis
1.B.164.1.5









Uncharacterized protein of 1362 aas with 2 strongly hydrophobic putative TMSs between residues 270 and 320, followed by 4 more putative TMSs of much lower hydrophobicity between residues 340 and 430.

Bacteria
Actinomycetota
UP of Microbacterium sp. GCS4
1.B.164.1.6









Uncharacterized protein of 496 aas and posibly 2 TMSs + several smaller hydrophobicity peaks that could be TMSs.

Bacteria
Pseudomonadota
UP of Vibrio cholerae
1.B.164.1.7









Uncharacterized protein of 499 aas and 4 putative TMSs between residues 240 and 330.

Bacteria
Actinomycetota
UP of Aeromicrobium sp. (soil metagenome)
1.B.164.1.8









Colicin D domain-containing protein of 453 aas and 2 TMSs between residues 160 and 320.

Bacteria
Actinomycetota
UP of Saccharopolyspora erythraea