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1.B.164.1.1 The nutrient outer membrane channel, CpnT, of 846 aas and 1 N=terminal TMS and possibly two more TMSs at about residues 220 and 270. It can be mutated to serve as a Ca2+ channel and promote cell death (D'Elia and Weinrauch 2023).
Accession Number:	O05442
Protein Name:	Outer membrane channel protein CpnT
Length:	846
Molecular Weight:	88335.00
Species:	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [83332]
Location¹ / Topology² / Orientation³:	Secreted¹
Substrate	calcium(2+), nutrient

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MAPLAVDPAA LDSAGGAVVA AGAGLGAVIS SLTAALAGCA GMAGDDPAGA VFGRSYDGSA 
61:	AALVQAMSVA RNGLCNLGDG VRMSAHNYSL AEAMSDVAGR AAPLPAPPPS GCVGVGAPPS 
121:	AVGGGGGAPK GWGWVAPYIG MIWPNGDSTK LRAAAVAWRS AGTQFALTEI QSTAGPMGVI 
181:	RAQQLPEAGL IESAFADAYA STTAVVGQCH QLAAQLDAYA ARIDAVHAAV LDLLARICDP 
241:	LTGIKEVWEF LTDQDEDEIQ RIAHDIAVVV DQFSGEVDAL AAEITAVVSH AEAVITAMAD 
301:	HAGKQWDRFL HSNPVGVVID GTGQQLKGFG EEAFGMAKDS WDLGPLRASI DPFGWYRSWE 
361:	EMLTGMAPLA GLGGENAPGV VESWKQFGKS LIHWDEWTTN PNEALGKTVF DAATLALPGG 
421:	PLSKLGSKGR DILAGVRGLK ERLEPTTPHL EPPATPPRPG PQPPRIEPPE SGHPAPAPAA 
481:	KPAPVPANGP LPHSPTESKP PPVDRPAEPV APSSASAGQP RVSAATTPGT HVPHGLPQPG 
541:	EHVPAQAPPA TTLLGGPPVE SAPATAHQPQ WATTPAAPAA APHSTPGGVH STESGPHGRS 
601:	LSAHGSEPTH DGASHGSGHG SGSEPPGLHA PHREQQLAMH SNEPAGEGWH RLSDEAVDPQ 
661:	YGEPLSRHWD FTDNPADRSR INPVVAQLME DPNAPFGRDP QGQPYTQERY QERFNSVGPW 
721:	GQQYSNFPPN NGAVPGTRIA YTNLEKFLSD YGPQLDRIGG DQGKYLAIME HGRPASWEQR 
781:	ALHVTSLRDP YHAYTIDWLP EGWFIEVSEV APGCGQPGGS IQVRIFDHQN EMRKVEELIR 
841:	RGVLRQ

1.B.164.1.1
The nutrient outer membrane channel, CpnT, of 846 aas and 1 N=terminal TMS and possibly two more TMSs at about residues 220 and 270. It can be mutated to serve as a Ca2+ channel and promote cell death (D'Elia and Weinrauch 2023).

Cross database links:

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Analyze:

1.B.164.1.1The nutrient outer membrane channel, CpnT, of 846 aas and 1 N=terminal TMS and possibly two more TMSs at about residues 220 and 270. It can be mutated to serve as a Ca2+ channel and promote cell death (D'Elia and Weinrauch 2023).

Cross database links:

External Searches:

Analyze:

1.B.164.1.1
The nutrient outer membrane channel, CpnT, of 846 aas and 1 N=terminal TMS and possibly two more TMSs at about residues 220 and 270. It can be mutated to serve as a Ca2+ channel and promote cell death (D'Elia and Weinrauch 2023).