TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.C.123.1.2
Gasdermin A of 445 aas.  Gasdermins A and B may be involved in asthma (Zihlif et al. 2016). Induction in the epidermis leads to skin inflammation (Lin et al. 2015). Roles of multiple charged residues in membrane insertion of gasdermin-A3 have been identified (Korn and Pluhackova 2022).

Accession Number:Q96QA5
Protein Name:Gasdermin-A
Length:445
Molecular Weight:49365.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate orobol

Cross database links:

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MTMFENVTRA LARQLNPRGD LTPLDSLIDF KRFHPFCLVL RKRKSTLFWG ARYVRTDYTL 
61:	LDVLEPGSSP SDPTDTGNFG FKNMLDTRVE GDVDVPKTVK VKGTAGLSQN STLEVQTLSV 
121:	APKALETVQE RKLAADHPFL KEMQDQGENL YVVMEVVETV QEVTLERAGK AEACFSLPFF 
181:	APLGLQGSIN HKEAVTIPKG CVLAFRVRQL MVKGKDEWDI PHICNDNMQT FPPGEKSGEE 
241:	KVILIQASDV GDVHEGFRTL KEEVQRETQQ VEKLSRVGQS SLLSSLSKLL GKKKELQDLE 
301:	LALEGALDKG HEVTLEALPK DVLLSKEAVG AILYFVGALT ELSEAQQKLL VKSMEKKILP 
361:	VQLKLVESTM EQNFLLDKEG VFPLQPELLS SLGDEELTLT EALVGLSGLE VQRSGPQYMW 
421:	DPDTLPRLCA LYAGLSLLQQ LTKAS