1.C.135.1.1 ShoB pore-forming toxin, also called RyfB or YphI, of 26 aas with 1 TMS. More is known about how their
expression is regulated than their biological function. Although all are found in E. coli and closely related bacteria, there is great variation
among species as to which loci they possess. Fozo 2012 discussed how
these sRNA antitoxins prevent toxin production and how the distribution
of these loci across species may be providing insights into their true
function. Overexpression causes cessation of growth and rapid
membrane depolarization. Overexpression induces the stress-response and the induction of a
number of membrane protein-encoding genes (Fozo et al. 2008).
|
Accession Number: | C1P611 |
Protein Name: | Small toxic protein ShoB |
Length: | 26 |
Molecular Weight: | 3103.00 |
Species: | Escherichia coli (strain K12) [83333] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Single-pass membrane protein2 |
Substrate |
inorganic ion |
---|
1: MTDCRYLIKR VIKIIIAVLQ LILLFL