1.C.14.1.7
Phobalysin (Cytolysin; Hemolysin; HlyA, PhlyP ("photobacterial lysin encoded on a plasmid") of 603 aas. 48% identical to The Vibrio cholerae hemolysin (1.C.14.1.1). Forms small β-barrel pores in eukaryotic membranes causing efflux of K+ and ATP but not proteins and entry of Ca2+ and dyes (Rivas et al. 2015; von Hoven et al. 2017).
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| Accession Number: | D1J6Q5 |
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| Protein Name: | Cytolysin and hemolysin, HlyA, Pore-forming toxin |
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| Length: | 603 |
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| Molecular Weight: | 68061.00 |
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| Species: | Photobacterium damselae subsp. damselae [85581] |
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| Number of TMSs: | 1 |
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| Substrate |
potassium(1+), ATP |
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1: MKIRKLYSCI LLGLSSLSAS AIAEVDNYST PADVVSILSS VKNPDRIVYI NMKQEELSTY
61: DSILEDIINN DKQYIFDLSF DSDEEKANLQ KKFKDLMGVK FDSNFIVVTG YKNQLMYTPI
121: SDTNDRMISI LDHEAKSNDI SKFPRALALS SGKVASDQSI SLPHVSFYLN VNKEITDQEC
181: TFRNSLIWDR GSRSFCKNGN ISLIYQVILE RSLSFGTNGV ATPDAKIVRI SLDDNTTGAG
241: IHLNDTLTHK SYWANYQVVS GWAREWSASA IAQDYLFDIS TSNEKAQILK TFPRENINSN
301: YNINESSGFT IGVTGGAEVS KDGPKASLQA SASYSQSKSL SFNTQDYRVE KNSTSAQNVS
361: FRWAREQYPN SESLLDKWTN PVWSEDYPAN LKKVQPLSYA SFVPKLDVIY KASPNETGKT
421: QFTIDSSVNI MPLYNRAWFY FYGVGAHQTY YGVDDQPLRR VNKAISFTVD WEHPVFTGGT
481: PVNIQLASFN NKCMDIQNKG IVMTAECDIN SKSQSFIYDQ YNRYVSATNT KLCLDGESLS
541: ELQPCSLKLT QKWLWDGDKL KNSFEDKYLT FDNDTFLLES SLSNKQKLNS SYTRVFDSST
601: INK