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1.C.2.1.1
ICP Cry1Aa. Cry1A (Receptors in Lepidoptera are cadherin-like proteins (Fabrick et al., 2009) but can also be ABC-type efflux pumps (Chen et al. 2018). The pore-forming mechanism has been studied by Groulx et al. (2010).  This toxin causes necrosis in Drosophila species (Obata et al. 2015).

Accession Number:P0A367
Protein Name:C1AA aka Cry1Aa aka CRYIA(A) aka CRY-1-1 aka CRYA aka ICP
Length:1176
Molecular Weight:133170.00
Species:Bacillus thuringiensis subsp. aizawai [1433]
Location1 / Topology2 / Orientation3: Secreted1
Substrate molecule

Cross database links:

Pfam: PF03944    PF00555    PF03945   

Gene Ontology

GO:0005102 F:receptor binding
GO:0006952 P:defense response
GO:0009405 P:pathogenesis
GO:0030435 P:sporulation resulting in formation of a cel...

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MDNNPNINEC IPYNCLSNPE VEVLGGERIE TGYTPIDISL SLTQFLLSEF VPGAGFVLGL 
61:	VDIIWGIFGP SQWDAFLVQI EQLINQRIEE FARNQAISRL EGLSNLYQIY AESFREWEAD 
121:	PTNPALREEM RIQFNDMNSA LTTAIPLFAV QNYQVPLLSV YVQAANLHLS VLRDVSVFGQ 
181:	RWGFDAATIN SRYNDLTRLI GNYTDYAVRW YNTGLERVWG PDSRDWVRYN QFRRELTLTV 
241:	LDIVALFSNY DSRRYPIRTV SQLTREIYTN PVLENFDGSF RGMAQRIEQN IRQPHLMDIL 
301:	NSITIYTDVH RGFNYWSGHQ ITASPVGFSG PEFAFPLFGN AGNAAPPVLV SLTGLGIFRT 
361:	LSSPLYRRII LGSGPNNQEL FVLDGTEFSF ASLTTNLPST IYRQRGTVDS LDVIPPQDNS 
421:	VPPRAGFSHR LSHVTMLSQA AGAVYTLRAP TFSWQHRSAE FNNIIPSSQI TQIPLTKSTN 
481:	LGSGTSVVKG PGFTGGDILR RTSPGQISTL RVNITAPLSQ RYRVRIRYAS TTNLQFHTSI 
541:	DGRPINQGNF SATMSSGSNL QSGSFRTVGF TTPFNFSNGS SVFTLSAHVF NSGNEVYIDR 
601:	IEFVPAEVTF EAEYDLERAQ KAVNELFTSS NQIGLKTDVT DYHIDQVSNL VECLSDEFCL 
661:	DEKQELSEKV KHAKRLSDER NLLQDPNFRG INRQLDRGWR GSTDITIQGG DDVFKENYVT 
721:	LLGTFDECYP TYLYQKIDES KLKAYTRYQL RGYIEDSQDL EIYLIRYNAK HETVNVPGTG 
781:	SLWPLSAQSP IGKCGEPNRC APHLEWNPDL DCSCRDGEKC AHHSHHFSLD IDVGCTDLNE 
841:	DLGVWVIFKI KTQDGHARLG NLEFLEEKPL VGEALARVKR AEKKWRDKRE KLEWETNIVY 
901:	KEAKESVDAL FVNSQYDQLQ ADTNIAMIHA ADKRVHSIRE AYLPELSVIP GVNAAIFEEL 
961:	EGRIFTAFSL YDARNVIKNG DFNNGLSCWN VKGHVDVEEQ NNQRSVLVVP EWEAEVSQEV 
1021:	RVCPGRGYIL RVTAYKEGYG EGCVTIHEIE NNTDELKFSN CVEEEIYPNN TVTCNDYTVN 
1081:	QEEYGGAYTS RNRGYNEAPS VPADYASVYE EKSYTDGRRE NPCEFNRGYR DYTPLPVGYV 
1141:	TKELEYFPET DKVWIEIGET EGTFIVDSVE LLLMEE