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Mastoparan (INWKKMAATALKMI).  Amiino acid substitutions gave rise to mastoparans that displayed a broad-spectrum antimicrobial activity against bacteria and fungi (MIC in the range 3-25μM), without being hemolytic or cytotoxic (Irazazabal et al. 2016).

Accession Number:P42716
Protein Name:MAST
Molecular Weight:1619.00
Species:Parapolybia indica [31921]
Location1 / Topology2 / Orientation3: Secreted1
Substrate molecule

Cross database links:

Pfam: PF08249   

Gene Ontology

GO:0005576 C:extracellular region
GO:0019835 P:cytolysis
GO:0019836 P:hemolysis by symbiont of host erythrocytes
GO:0043303 P:mast cell degranulation

References (1)

[1] “Structural and biological characterization of three novel mastoparan peptides from the venom of the neotropical social wasp Protopolybia exigua (Saussure).”  Mendes   15581688

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