1.C.4.5.2
Fhb1 protein (PFT gene product) of 478 aas with two agglutinin domains followed by a DON (ETX/MTX2) domain that has the toxin activity (Rawat et al. 2016). Counteracts Fusarium head blight (FHB), caused by Fusarium graminearum, a devastating disease of wheat and barley. The fungicidal mechanism of glabridin, an isoflavane, a type of isoflavonoid, against Fusarium graminearum, showed that it acts on ergosterol synthesis-related proteins to destroy the integrity of the cell membrane, resulting in abnormal transmembrane transport and an increased membrane potential (Yang et al. 2021).
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| Accession Number: | AOZ21512 |
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| Protein Name: | AOZ21512.1 putative agglutinin protein [Triticum aestivum] |
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| Length: | 479 |
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| Molecular Weight: | |
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| Species: | Triticum aestivum [4565] |
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| Substrate |
small molecules |
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1: MFPLSALPRC VALRSKHGNS YLRSVHDKSQ GGNFVELSAD NDGGVMNPRC RFYLEASKEH
61: DGLVHVRCCY NNKYWAPQQR LLHGSARWTI GTANELEEDL SKPSCTLFKH IPVSGEDGST
121: CRFLHSQLGK YACVLSSSDM SKHPYLHIAR EESDQDNLLD AFTVLDVSEQ MQLPSYLAFK
181: GDNGRFLGAK IVEGYRYLEY SKDDIGDLSV LHTIFTNKDG VVRIKSNYFD MFWRRSPNWI
241: WADSTDTTHN NRDTLFKVTT GPDFIALRNL GNNNFCKRLT TEGKYDCLNA AVGSITAEVK
301: MRCIEPIVSR DIYDVDFRLG EAKIYTNGIE GLDSQIVENM TTTTNKTKMI FTYTNTVQST
361: WSSTVSLKIG VKTKFKSGIP FVVDGEVEVS TEFSGSYTWG GAKSDTKVVS KQIDVEVPPM
421: KKVTVKAIGS NGLCDIPFSY KQRDILTNGD EVIQEFTDGM YFGVKTSSIT FHTKEEHL