TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.C.52.1.11
Preprofallaxidin-6 (green tree frog) (71% identical to 1.C.52.1.9).  The NMR structure of the mature peptide (Fallaxidin 4.1a) reveals a helical structure in detergent solultions.  Pore formation is established (Sherman et al. 2009).

Accession Number:B5LUQ8
Protein Name:Preprofallaxidin-6
Length:103
Molecular Weight:11991.00
Species:Litoria fallax (Eastern dwarf tree frog) [115422]
Location1 / Topology2 / Orientation3: Secreted1
Substrate ion

Cross database links:

Pfam: PF03032   

Gene Ontology

GO:0005576 C:extracellular region
GO:0042742 P:defense response to bacterium

References (1)

[1] “The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.”  Jackway R.J.et.al.   18803332

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MASLKKSLFL VLFLGFVSLS ICEEEKRENE GNENEEEDEN HEEGSEEKRG LLDLAKHVIG 
61:	IASKLGKRSE EKRYHPFGKR SEEKRYHPFG KRSEEKRYPP IGK