TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.C.52.1.1









Dermaseptin B1 precursor

Eukaryota
Metazoa
Dermaseptin B1 of Phyllomedusa bicolor
1.C.52.1.2









Brevinin 2EF precursor
Eukaryota
Metazoa
Brevinin-2EF of Rana esculenta
1.C.52.1.3









Gaegurin-4 precursor
Eukaryota
Metazoa
Gaegurin-4 of Rana rugosa
1.C.52.1.4









Esculentin-1b precursor
Eukaryota
Metazoa
Esculentin-1b of Rana esculenta
1.C.52.1.5









Temporin G precursor
Eukaryota
Metazoa
Temporin G precursor of Rana temporaria
1.C.52.1.6









Temporin B precursor
Eukaryota
Metazoa
Temporin B precursor of Rana temporaria
1.C.52.1.7









Ranatuerin-2P precursor
Eukaryota
Metazoa
Ranatuerin-2P precursor of Rana pipiens
1.C.52.1.8









Tryptophyllin-1 precursor
Eukaryota
Metazoa
Tryptophyllin-1 precursor of Pachymedusa dacnicolor
1.C.52.1.9









Caerin 1.1.5 precursor; similar to maculatin 1.1 of Litoria genimaculata (1.C.76.1.1) (Fernandez et al., 2008; Mechler et al., 2007).
Eukaryota
Metazoa
Caerin 1.1.5 precursor of Litoria caerulea
1.C.52.1.10









PBN1 precursor
Eukaryota
Metazoa
PBN1 precursor of Phyllomedusa bicolor
1.C.52.1.11









Preprofallaxidin-6 (green tree frog) (71% identical to 1.C.52.1.9).  The NMR structure of the mature peptide (Fallaxidin 4.1a) reveals a helical structure in detergent solultions.  Pore formation is established (Sherman et al. 2009).

Eukaryota
Metazoa
Fallaxidin of Litoria fallax (B5LUQ8)
1.C.52.1.12









Phylloseptin-7 (orange legged leaf frog) (81% identical to 1.C.52.1.10).
Eukaryota
Metazoa
Phylloseptin of Phyllomedusa hypochondrialis (P84572)
1.C.52.1.13









Raniseptin-1 (55% identical to 1.C.52.1.1).
Eukaryota
Metazoa
Raniseptin-1 of Hypsiboas raniceps (P86037)
1.C.52.1.14









Kininogen-1 (71% identical to 1.C.52.1.10).
Eukaryota
Metazoa
Kininogen-1 of Phyllomedusa sauvagei (Q800F1).
1.C.52.1.15









Vespakinin-M precursor (also homologous to Melittin)
Eukaryota
Metazoa
Vespakinin of Vespa magnifica (Q0PQX8)
1.C.52.1.16









Brevienin-1E of 71 aas

Eukaryota
Metazoa
Brevenin-iE of Pelophylex esulentus
1.C.52.1.17









Ranakinin-N of 58 aas

Eukaryota
Metazoa
Ranakinin-N of Hylarana nigrovittata
1.C.52.1.18









Prepromelittin amphibian defense peptide

Eukaryota
Metazoa
Prepromelittin of Rana andersonii (E3SZK1)
1.C.52.1.19









Rufosusi-spotted torrent frog Amolopin-3a anti-microbial peptide

Eukaryota
Metazoa
Amolopin-3a of Amolops loloensis (A6XFB5)
1.C.52.1.20









Demaseptin-1

Eukaryota
Metazoa
Dermaseptin-1 of Phyllomedusa hypochondrialis (P84596)
1.C.52.1.21









Brevinin-2HS of 70 aas and 2 TMSs.

Eukaryota
Metazoa
Brevinin-2HS of Odorrana schmackeri (Schmacker's frog) (Rana schmackeri)
1.C.52.1.22









Rhacophorin-2 of 72 aas and 2 TMSs.

Eukaryota
Metazoa
Rhacophori-2 of Rhacophorus feae (Thao whipping frog)
1.C.52.1.23









Hainanensin-1 of 67 aas and 2 TMSs

Eukaryota
Metazoa
Hainanensin-1 of Odorrana hainanensis (Odor frog) (Rana hainanensis)
1.C.52.1.24









Amurin-1 of 70 aas and 2 TMSs

Eukaryota
Metazoa
Amurin-1 of Rana amurensis (Korean brown frog)
1.C.52.1.25









Viridimin-1 of 66 aas and 2 TM

Eukaryota
Metazoa
Viridimin-1 of Amolops viridimaculatus (Dahaoping sucker frog)
1.C.52.1.26









Amolopin-1a of 70 aas

Eukaryota
Metazoa
Amolopin-1a of Amolops loloensis (rufous-spotted torrent frog)
1.C.52.1.27









Andersonin of 72 aas

Eukaryota
Metazoa
Andersonin of Odorrana andersonii (golden crossband frog)
1.C.52.1.28









Lividin-1 of 68 aas

Eukaryota
Metazoa
Lividin-1 of Odorrana livida (green cascade frog)
1.C.52.1.29









Kunyuenin of 62 aas

Eukaryota
Metazoa
Kunyuenin of Rana kunyuensis
1.C.52.1.30









Japonicin-1Ja of 61 aas

Eukaryota
Metazoa
Japonicin-1Ja of Rana japonica (Japanese reddish frog)
1.C.52.1.31









Limnonectin-1Fa of 62 aas

Eukaryota
Metazoa
Limnonectin-1Fa of Limnonectes fujianensis (Fujian large-headed frog)
1.C.52.1.32









Jingdongin-1 of 63 aas

Eukaryota
Metazoa
Jingdongin-1 of Amolop jingdongensis (Chinese torrent frog)
   
1.C.52.1.33









Frenatin-3 of 68 aas

Eukaryota
Metazoa
Frenatin-2 of Litoria infrafrenata (Giant tree frog) (White-lipped tree frog)
1.C.52.1.34









Antimicrobial peptide odorranain B4 of 63 aas.  A 15 aa disulfide bonded peptide, ORB-1 (LKGCWTKSIPPKPCF), too short to pass through a membrane, forms anion selective channels (Hu et al. 2015).

Eukaryota
Metazoa
odorranain B4 of Odorrana grahami (Yunnanfu frog) (Rana grahami)
1.C.52.1.35









Pore-forming Ocellatin-PT1 of 66 aas (Gusmão et al. 2017).

Eukaryota
Metazoa
Ocellatin-PT1 of Leptodactylus pustulatus (Ceara white-lipped frog)
1.C.52.1.36









Dybowskin-1ST antimicrobial peptide of 59 aas. It has an N-terminal TMS with a largely hydrophilic central region with an α-helical structure. It promotes wound healing and effectively inhibits the growth of Escherichia coli and Staphylococcus aureus (Liu et al. 2021).

 

Eukaryota
Opisthokonta
antimicrobial peptide of Rana dybowskii (Dybovsky's frog) (Korean brown frog)
1.C.52.2.1









Ceratotoxin A, CtxA, of 72 aas and 2 TMSs.  It forms one of the largest pores among the group of ceratotoxins (Mayer et al. 2019).

Eukaryota
Metazoa
CtxA of Ceratitis capitata (medfly) (P36190)
1.C.52.2.2









Ceratotoxin-B of 29 aas, corresponding to the C-terminal region of Ceratotoxin A.

Eukaryota
Opisthokonta
Ceratotoxin-B of Ceratitis capitata (Mediterranean fruit fly)
1.C.52.2.3









Ceratotoxin 2 of 40 aas and 1 N-terminal TMS.

Eukaryota
Opisthokonta
Ceretotoxin 2 of Ceratitis rosa (Natal fruit fly)