TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.C.52.2.1
Ceratotoxin A, CtxA, of 72 aas and 2 TMSs.  It forms one of the largest pores among the group of ceratotoxins (Mayer et al. 2019).

Accession Number:P36190
Protein Name:CtxA1 aka Ceratotoxin A precursor 1
Length:71
Molecular Weight:7151.00
Species:Ceratitis capitata (Mediterranean fruit fly) [7213]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Secreted1
Substrate ion

Cross database links:

Gene Ontology

GO:0005576 C:extracellular region
GO:0019835 P:cytolysis
GO:0042742 P:defense response to bacterium
GO:0019836 P:hemolysis by symbiont of host erythrocytes
GO:0045087 P:innate immune response

References (2)

[1] “cDNA sequence and expression of the ceratotoxin gene encoding an antibacterial sex-specific peptide from the medfly Ceratitis capitata (diptera).”  Marchini D.et.al.   7890755
[2] “Purification and primary structure of ceratotoxin A and B, two antibacterial peptides from the female reproductive accessory glands of the medfly Ceratitis capitata (Insecta: Diptera).”  Marchini D.et.al.   8353519

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MANLKAVFLI CIVAFIALQC VVAEPAAEDS VVVKRSIGSA LKKALPVAKK IGKIALPIAK 
61:	AALPVAAGLV G