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1.C.58.1.1
Microcin E492 (Bieler et al., 2006).  Exhibits anti-bacterial and anti-tumor activities due to pore formation (Lagos et al. 2009).

Accession Number:Q9Z4N4
Protein Name:MCEA
Length:99
Molecular Weight:9562.00
Species:Klebsiella pneumoniae, Escherichia coli [573]
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Lipid-anchor2
Substrate cation

Cross database links:

Gene Ontology

GO:0005216 F:ion channel activity
GO:0005102 F:receptor binding
GO:0019835 P:cytolysis
GO:0042742 P:defense response to bacterium
GO:0006811 P:ion transport

References (5)

[1] “Identification and properties of the genes encoding microcin E492 and its immunity protein.”  Lagos R.et.al.   9864332
[2] “Microcin E492 is an unmodified peptide related in structure to colicin V.”  Pons A.-M.et.al.   11751140
[3] “Microcin E492 antibacterial activity: evidence for a TonB-dependent inner membrane permeabilization on Escherichia coli.”  Destoumieux-Garzon D.et.al.   12890026
[4] “Siderophore peptide, a new type of post-translationally modified antibacterial peptide with potent activity.”  Thomas X.et.al.   15102848
[5] “Microcin E492 forms ion channels in phospholipid bilayer membrane.”  Lagos R.et.al.   7682973

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MREISQKDLN LAFGAGETDP NTQLLNDLGN NMAWGAALGA PGGLGSAALG AAGGALQTVG 
61:	QGLIDHGPVN VPIPVLIGPS WNGSGSGYNS ATSSSGSGS