1.C.74.1.6
3 finger muscarinic toxin, Mt1 of 66 aas. Shows a non-competitive interaction with adrenergic and muscarinic receptors. Binds to alpha-2b (ADRA2B) (IC50=2.3
nM), alpha-1a (ADRA1A), alpha-1b (ADRA1B), and alpha-2c (ADRA2C)
adrenergic receptors. Reversibly binds to M1 (CHRM1) muscarinic
acetylcholine receptors, probably by interacting with the orthosteric
site.
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| Accession Number: | P81030 |
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| Protein Name: | Three-finger muscarinic toxin 1 |
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| Length: | 66 |
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| Molecular Weight: | 7518.00 |
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| Species: | Dendroaspis angusticeps (Eastern green mamba) [8618] |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
ion, molecule |
|---|
1: LTCVTSKSIF GITTENCPDG QNLCFKKWYY IVPRYSDITW GCAATCPKPT NVRETIRCCE
61: TDKCNE