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1.D.100.  The Leucine (L)-Lysine (K) Synthetic Peptide Channel-forming (LK-SPC) Family

Several peptides containing only Leucine and lysine, organized so that the Ks all appear on one side of an α-helix, have been synthesized and examined for their nanopore properties.  The four peptides studied all formed transmembrane pores and conducted ions (Sekiya et al. 2018):





References associated with 1.D.100 family:

Sekiya, Y., S. Sakashita, K. Shimizu, K. Usui, and R. Kawano. (2018). Channel current analysis estimates the pore-formation and the penetration of transmembrane peptides. Analyst. [Epub: Ahead of Print] 29790494