1.D.155. The Toroidal Type Ion Pore-forming Taxol (Taxol) Family
Taxol (paclitaxel) is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug that is classified as a "plant alkaloid", a "taxane" and an "antimicrotubule agent" (Peltier et al. 2006). It forms toroidal pores in lipid bilayers. The antimicrobial peptide, gramicidin S, enhances membrane adsorption and ion pore formation potency of taxol in lipid bilayers (Ashrafuzzaman 2021).