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1.D.178.  The Semiaza-Bambusuril (Semiaza-Bambusuril) Family 

Semiaza-Bambus[6]urils efficiently transport anions across lipid membranes. A systematic modification of their lipophilic side chains to include various alkyl groups and thioethers revealed that the most efficient chloride transporters are those that agree with Lipinski's rule-of-lipophilicity, exhibiting clog Po/w values close to 5. Furthermore, vesicle anion-transport assays showed that these anion-transporters function independently of the cation. They exhibit high anion selectivity, NO3- > Br- > Cl- > SO42-, in agreement with the Hofmeister series. These compounds may be used to allow for the design of highly specific anion transporters for biomedical applications (Khurana et al. 2022).

References associated with 1.D.178 family:

Khurana, R., F. Yang, R. Khurana, J. Liu, E. Keinan, and O. Reany. (2022). -Bambusurils are anion-specific transmembrane transporters. Chem Commun (Camb) 58: 3150-3153. 35170624