1.E.52 The Flp/Fap Pilin Putative Holin (FFPP-Hol) Family

The FFPP family is a large diverse family with members from many bacterial phyla.  Some members are annotated as Flp or Fap pilin subunits; others are identified as Holin BlyA family members.  They have sizes of 50 - 80 aas with a single N-terminal TMS although one member has 99 aas and 2 TMSs.  Flp homologues are included in TCDB under TC# 3.A.7.13.1 (pXO1-63) and TC# 3.A.7.15.1 (Flp-1).  Their precise functions appear to be unknown.