1.F.3. The EH Domain-containing Protein 1 (ETMP1) Family
ETMP1 is an ATP- and membrane-binding protein that controls membrane reorganization and tubulation upon ATP hydrolysis. In vitro, it causes vesiculation of endocytic membranes (Cai et al. 2013). It acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (Rahajeng et al. 2010). Lipid and ion transport, mitosome fission, and quality control are potential processes that are mediated by the ETMP1-EHD1-tethered mitosome-endosome contact site in E. histolytica (Santos et al. 2022).