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1.G.17 The Bovine Leukemia Virus Envelope Glycoprotein (BLV-Env) Family

This family includes envelop glycoproteins of variable sizes due to proteolytiprocessing.  The actual fusion peptide is 24 aas long (Apellániz et al. 2014).  It derives from gPr72 of 341 aas which is an Env protein fragment that is further degraded to the envelope glycoprotein, Env-GP of 127 aas (acc# L0R354) and then to the fusion peptide.

References associated with 1.G.17 family:

Apellaniz B., Huarte N., Largo E. and Nieva JL. (2014). The three lives of viral fusion peptides. Chem Phys Lipids. 181:40-55. 24704587
Matsuura, R., K. Inabe, H. Otsuki, K. Kurokawa, N. Dohmae, and Y. Aida. (2019). Three YXXL Sequences of a Bovine Leukemia Virus Transmembrane Protein are Independently Required for Fusion Activity by Controlling Expression on the Cell Membrane. Viruses 11:. 31835517
Meher, G. and H. Chakraborty. (2020). The role of fusion peptides in depth-dependent membrane organization and dynamics in promoting membrane fusion. Chem Phys Lipids 234: 105025. [Epub: Ahead of Print] 33301753
Wilson, K.A., S. Bär, A.L. Maerz, M. Alizon, and P. Poumbourios. (2005). The conserved glycine-rich segment linking the N-terminal fusion peptide to the coiled coil of human T-cell leukemia virus type 1 transmembrane glycoprotein gp21 is a determinant of membrane fusion function. J. Virol. 79: 4533-4539. 15767455