1.G.2.1.6
Fusion glycoprotein of 529 aas (Apellániz et al. 2014). Loosely
associated fusion peptide and TMS helices generate significant negative Gaussian curvature to
membranes that possess spontaneous positive curvature, consistent with fusion peptide-TMS
assembly facilitating the transition of the membrane from hemifusion intermediates to the fusion
pore (Yao et al. 2016).
|
| Accession Number: | W5QKP1 |
|---|
| Protein Name: | Fusion glycoprotein F0 |
|---|
| Length: | 529 |
|---|
| Molecular Weight: | 56627.00 |
|---|
| Species: | Parainfluenza virus 5 [11207] |
|---|
| Number of TMSs: | 4 |
|---|
| Location1 / Topology2 / Orientation3: |
Virion membrane1 / Single-pass type I membrane protein2 |
|---|
| Substrate |
molecule |
|---|
1: MGTIIQFLVV SCLLAGAGSL DPATLMQIGV IPTNVRQLMY YTEASSAFIV VKLMPTIDSP
61: ISGCNITSIS SYNATVTKLL QPIGENLETI RNQLIPTRRR RRFAGVVIGL AALGVATAAQ
121: VTAAVALVKA NENAAAILNL KNAIQKTNAA VADVVQATQS LGTAVQAVQD HINSVVSPAI
181: TAANCKAQDA IIGSILNLYL TELTTIFHNQ ITNPALSPIT IQALRILLGS TLPTVVEKSF
241: NTQISAAELL SSGLLTGQIV GLDLTYMQMV IKIELPTLTV QPATQIIDLA TISAFINNQE
301: VMAQLPTRVM VTGSLIQAYP ASQCTITPNT VYCRYNDAQV LSDDTMACLQ GNLTRCTFSP
361: VVGSFLTRFV LFDGIVYANC RSMLCKCMQP AAVILQPSSS PVTVIDMYKC VSLQLDNLRF
421: TITQLANVTY NSTIKLESSQ ILSIDPLDIS QNLAAVNKSL SDALQHLAQS DTYLSAITSA
481: TTTSVLSIIA ICLGSLGLIL IILLSVVVWK LLTIVVANRN RMENFVYHK