1.G.2.1.9
The fusion (F) protein (602 aas and 3 very hydrophobic TMSs, one N-terminal, one at residue 120 and one C-terminal, plus 5 moderately hydrophobic peaks at residies 240 - 470, of the zoonotic Nipah virus, that together with the G (glyco)-protein (546 aas and 1 N-terminal TMS; Q9IH62) are essential for viral entry into human and animal cells (Coropceanu et al. 2022).
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| Accession Number: | Q9IH63 |
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| Protein Name: | Fusion glycoprotein F0 |
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| Length: | 546 |
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| Molecular Weight: | 60282.00 |
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| Species: | Nipah virus [121791] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Virion membrane1 / Single-pass type I membrane protein2 |
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| Substrate |
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1: MVVILDKRCY CNLLILILMI SECSVGILHY EKLSKIGLVK GVTRKYKIKS NPLTKDIVIK
61: MIPNVSNMSQ CTGSVMENYK TRLNGILTPI KGALEIYKNN THDLVGDVRL AGVIMAGVAI
121: GIATAAQITA GVALYEAMKN ADNINKLKSS IESTNEAVVK LQETAEKTVY VLTALQDYIN
181: TNLVPTIDKI SCKQTELSLD LALSKYLSDL LFVFGPNLQD PVSNSMTIQA ISQAFGGNYE
241: TLLRTLGYAT EDFDDLLESD SITGQIIYVD LSSYYIIVRV YFPILTEIQQ AYIQELLPVS
301: FNNDNSEWIS IVPNFILVRN TLISNIEIGF CLITKRSVIC NQDYATPMTN NMRECLTGST
361: EKCPRELVVS SHVPRFALSN GVLFANCISV TCQCQTTGRA ISQSGEQTLL MIDNTTCPTA
421: VLGNVIISLG KYLGSVNYNS EGIAIGPPVF TDKVDISSQI SSMNQSLQQS KDYIKEAQRL
481: LDTVNPSLIS MLSMIILYVL SIASLCIGLI TFISFIIVEK KRNTYSRLED RRVRPTSSGD
541: LYYIGT