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The gO or gL glycoprotein fusogen of 278 aas and 3 TMSs, 1 N-terminal and 2 near the C-terminus (Feng and Jia 2016). The heterodimer glycoprotein H (742 aas; 2 TMSs, N- and C-terminal)-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB (907 aas; 3 TMSs, 1 N-terminal and 2 near the C-terminus; similar to gB of 1.G.10.1.1) and the heterodimer gH/gL.

gO of Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)