TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.G.4.1.1









The Semliki Forest Virus (SFV) (Class II) Structural polyprotein (1253 aas; E1=816-1253 E2=334-774).  The fusion peptide is residues 895 - 913 (Apellániz et al. 2014). The 6K viroporin transports monovalent cations and Ca2+ (Hyser and Estes 2015). Conformational change and protein-protein interactions of this fusion protein have been considered (Gibbons et al. 2004).

Viruses
Orthornavirae, Kitrinoviricota
Structural polyprotein of Semliki Forest Virus (P03315)
1.G.4.1.2









The Ross River virus 6K protein.  The class II fusion peptide is residues 896 - 914 (Apellániz et al. 2014).  The 6K protein transports monovalent cations and Ca2+ (Hyser and Estes 2015).

Viruses
Orthornavirae, Kitrinoviricota
6K protein of Ross River Virus (P08491)
1.G.4.1.3









The Barmah Forest virus 6K protein (58 aas; present within the viral structural polyprotein (P89946))
Viruses
Orthornavirae, Kitrinoviricota
6K protein of Barmah Forest Virus (P89946)
1.G.4.1.4









The Sindbis virus 6K protein (55 aas; present within the structural polyprotein (AAC83379)).  Transports monovalent cations and Ca2+ (Hyser and Estes 2015).

Viruses
Orthornavirae, Kitrinoviricota
6K protein of Sindbis Virus (Q9YJX7)
1.G.4.1.5









Salmonid α-virus 6K protein of 1319 aas and 6 TMSs in a possible 1 + 4 + 1 TMS arrangement (Elmasri et al. 2022).

Viruses
Orthornavirae, Kitrinoviricota
6K protein of Salmonid virus
1.G.4.1.6









Structural polyprotein, E2-6K-E1 region of 923 aas and 5 TMSs in a 4 (central) + 1 (C-terminal) TMS arrangement (Huang and Fischer 2022).

Viruses
Orthornavirae, Kitrinoviricota
E2-6K-E1 polyproptein of Chikungunya virus (CHIIKV).