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1.N.5.1.2
Atlastin of 541 aas and 2 TMSs near the C-terminus of the protein.  It is a GTPase, tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes (Orso et al. 2009). It functions in endoplasmic reticulum tubular network biogenesis and may also regulate microtubule polymerization and Golgi biogenesis. It is required for dopaminergic neurons survival and the growth of muscles and synapses at neuromuscular junctions (Lee et al. 2009).

Accession Number:Q9VC57
Protein Name:Atlastin
Length:541
Molecular Weight:60912.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Structure:
3X1D     

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGGSAVQVIN ASEEHTFVLN EDALSEVLMR DEVKDRFVCV VSVAGAFRKG KSFLLDFFLR 
61:	YMYSKYVHHD ATDWLGGESD PLEGFSWRGG SERDTTGILM WSDIFLHDYP NGDKIAIILL 
121:	DTQGAFDSQS TVRDCATVFA LSTMLSSVQI YNLSQNIQED DLQHLQLFTE YGRLALADTG 
181:	KKPFQRLQFL VRDWSFPYEA EYGALGGDKI LKRRLEVSDK QHPELQSLRR HISSCFTEVA 
241:	CFLMPHPGLN VATNPKFDGR LQDITPEFKS SLRSLVPMLL APDNLVYKEI SGQRVRARDL 
301:	IQYFQSYMNI YKGNELPEPK SMLVATAEAN HLTAVAAAKE LYGQLMEEVC GGTRPYLSTA 
361:	HLQTEHLRVK DKALFQFAAK RKMGGEEFTE KFRKQLEDDL EEVFTNYQAH NESKNIFKAA 
421:	RTPAVYFACA VIMYILSGIF GLVGLYTFAN FCNLVMGVAL LTLALWAYIR YSGELSDFGG 
481:	KLDDFATLLW EKFMRPIYHG CMEKGIHHVA THATEMAVGG GAASYRSQTS VNASNGKVKR 
541:	S