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2.A.1.1.111 High-affinity glucose transporter HXT2. Asp340 and Asn331 in part determine the high glucose affinity (Kasahara et al. 2007; Kasahara and Kasahara 2010).
Accession Number:	P23585
Protein Name:	High-affinity glucose transporter HXT2
Length:	541
Molecular Weight:	59841.00
Species:	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	glucose

DIP:	DIP-7912N
Entrez Gene ID:	855023
Pfam:	PF00083
KEGG:	sce:YMR011W
Gene Ontology GO:0016021 C:integral to membrane GO:0005624 C:membrane fraction GO:0005886 C:plasma membrane GO:0005353 F:fructose transmembrane transporter activity GO:0005355 F:glucose transmembrane transporter activity GO:0015578 F:mannose transmembrane transporter activity GO:0015146 F:pentose transmembrane transporter activity
References (6) [1] “The HXT2 gene of Saccharomyces cerevisiae is required for high-affinity glucose transport.” Kruckeberg A.L.et.al. 2233722 [2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.” Bowman S.et.al. 9169872 [3] “Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae.” Ficarro S.B.et.al. 11875433 [4] “A global topology map of the Saccharomyces cerevisiae membrane proteome.” Kim H.et.al. 16847258 [5] “Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.” Li X.et.al. 17330950 [6] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.” Albuquerque C.P.et.al. 18407956

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MSEFATSRVE SGSQQTSIHS TPIVQKLETD ESPIQTKSEY TNAELPAKPI AAYWTVICLC 
61:	LMIAFGGFVF GWDTGTISGF VNQTDFKRRF GQMKSDGTYY LSDVRTGLIV GIFNIGCAFG 
121:	GLTLGRLGDM YGRRIGLMCV VLVYIVGIVI QIASSDKWYQ YFIGRIISGM GVGGIAVLSP 
181:	TLISETAPKH IRGTCVSFYQ LMITLGIFLG YCTNYGTKDY SNSVQWRVPL GLNFAFAIFM 
241:	IAGMLMVPES PRFLVEKGRY EDAKRSLAKS NKVTIEDPSI VAEMDTIMAN VETERLAGNA 
301:	SWGELFSNKG AILPRVIMGI MIQSLQQLTG NNYFFYYGTT IFNAVGMKDS FQTSIVLGIV 
361:	NFASTFVALY TVDKFGRRKC LLGGSASMAI CFVIFSTVGV TSLYPNGKDQ PSSKAAGNVM 
421:	IVFTCLFIFF FAISWAPIAY VIVAESYPLR VKNRAMAIAV GANWIWGFLI GFFTPFITSA 
481:	IGFSYGYVFM GCLVFSFFYV FFFVCETKGL TLEEVNEMYV EGVKPWKSGS WISKEKRVSE 
541:	E

2.A.1.1.111
High-affinity glucose transporter HXT2. Asp340 and Asn331 in part determine the high glucose affinity (Kasahara et al. 2007; Kasahara and Kasahara 2010).

Cross database links:

Gene Ontology

References (6)

External Searches:

Analyze:

2.A.1.1.111High-affinity glucose transporter HXT2. Asp340 and Asn331 in part determine the high glucose affinity (Kasahara et al. 2007; Kasahara and Kasahara 2010).

Cross database links:

Gene Ontology

References (6)

External Searches:

Analyze:

2.A.1.1.111
High-affinity glucose transporter HXT2. Asp340 and Asn331 in part determine the high glucose affinity (Kasahara et al. 2007; Kasahara and Kasahara 2010).