2.A.1.1.125
Glycerol:H+ symporter of 530 aas and 12 TMSs, GT1. It is essnetial for the glycerol repression of the alcohol oxidase 1 (AOX1 gene (Zhan et al. 2016), and plays a role in glycerol and methanol metabolism in Pichia pastoris (Li et al. 2017).
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| Accession Number: | C4QVV9 |
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| Protein Name: | Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation |
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| Length: | 530 |
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| Molecular Weight: | 58804.00 |
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| Species: | Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) [644223] |
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| Number of TMSs: | 12 |
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| Substrate |
glycerol |
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1: MAIYSQPVRT HLIYNRRIML KLFQYQDFLR GKSFLWAITL CALQGFLLLG YDQGVMSCLI
61: SDPTFNKFFK YPNEDLQGDI TGTYDLGCVA GSIFCYFFGE QLGRRKALIL GGTIMVIGTV
121: FLGAANGVGI FIAGRVITGI GNGINSSTVP TLQAECSPAN IRGALLTLQG TVTILGLVIA
181: YWAGFGTSFV DSNFQWRFPV SFQAFFAVCL VIQAIGLPDT PRWLVAHGRL NEARNVIACL
241: LDKSEDDPEV ESQLFDIKTT VDEEFAGGPF KFKEFLQMGK TQNFRRLCIT IGVNIMQQFT
301: GSNMINYYAP TVYQKTMGFD NQMSMILGGC TSITYLVGSV LPVFLVDRFG RRTLLMVSAG
361: GLCFCFMMVS ILLSTEIQAA AYAAVAFIFI FQIFLAVGFL PVPWFLGSEL NITRLRARAC
421: SIASGWNWMC VYAIVKITPI AMKNLGWKTF IIFTVLNAMW IPIVYCFFPE TNGLELEDID
481: LIFARGGFTG GVFSTRGKTV QKHAHLNQQL KTGDEKDTGD IEFVEDVSRA