2.A.1.1.133 Facilitative glucose transporter, GLUT2 of 503 aas and 12 TMSs. Evidence suggests that the blunt snout bream is able to regulate its ability to metabolize glucose by improving GLUT2, GK, and PK expression levels (Liang et al. 2018). The ortholog in grass carp (Ctenopharyngodon idellus) is exactly the same size and 98% identical throughout its length. It is found in the anterior and mid intestine as well as the liver (Liang et al. 2020).
|
Accession Number: | N0A4A7 |
Protein Name: | Glucose transporter 2 |
Length: | 503 |
Molecular Weight: | 55046.00 |
Species: | Megalobrama amblycephala (Chinese blunt snout bream) [75352] |
Number of TMSs: | 11 |
Substrate |
D-glucopyranose |
---|
1: MEKQLTGTLA LAVFTAALGS LQMGYSLGVI NAPQKVIERH YARSLGVYDE NLSRREGGNA
61: TEHEEPSDPS VVMYWSLSVA IFSIGGMVSS FLVSFVSDFR GRIKGMLAIN VLAITAGLLM
121: GLAKMGTPYL MVIAGRAIMG LYCGLSSGLV PLYIGEISPM KFRGAMGALH QLAIVIGILI
181: SQVIGLEFLL GNDDMWHVLL GLSGAPAILQ SLLLLLCPES PRYLYIKQGK VEEACKNLKR
241: LKGDYDTSKD IAEMQAEKEE AMKEAKMSIW RLLRSSVYRQ QLFVALMMHF SQQFSGINAI
301: FYYSTSIFQT AGVGQPVYAT IGVGVINIIF TLVSVILVDR TGRRTLTLVG LGGMCCCAVA
361: MTVGLAFQDV YSWMSYLSMT AIFLFVSFFE IGPGPIPWFI VAELFSQGPR PAAIALAGCC
421: NWTCNFIIGM FFPYLEGLCG SYVFVIFAVL LFGFTVFIYL RVPETKGKTF EEIAAVFHHK
481: RGAPPSKPQE EAEMVQLKSS TEA