2.A.1.1.144
Facilitative glucose transporter 4, GLUT4, of 505 aas and 12 TMSs. MaGLUT4 is mainly distributed in muscle. Changes in the insulin, mRNA, and protein levels of MaGUT4 lagged far behind changes in blood glucose levels. This delay in insulin level changes and GLUT4 activation might be the reason for glucose intolerance of this fish species (Liang et al. 2020).
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| Accession Number: | QLE11221 |
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| Protein Name: | QLE11221.1 facilitative glucose transporter 4 [Megalobrama amblycephala] |
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| Length: | 506 |
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| Molecular Weight: | |
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| Species: | Megalobrama amblycephala [75352] |
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| Number of TMSs: | 12 |
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| Substrate |
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1: MPAGFQQLGG ERITGTLALS VFTAVLGSLQ FGYNIGVINA PQKIIEQDYN STWTERYSEP
61: IPLQTLTSLW SLSVAIFSIG GMVSSFSVGI ISEFFGRRKA MLINNVLAFI GGGLMGMSKI
121: SRSFEMMILG RFTIGAYCGL ASGLVPMYVG EIAPTSLRGA LGTLHQLAIV TGILIAQILG
181: LESLLGSEQL WPVLLGVTVL PTVLQMTLLP FCPESPRFLY IIRCQEHHAK SALRRLTGRM
241: EVSEDLAEMK EEKRRMEMER KVSIAELFRS PLYRQPIIIA ILLQLSQQLS GVNAIFYYST
301: DIFKKAGVES PVYATIGAGV VNCAFTIVSL FLIERMGRRT LHMLGLAGMC ICAIIMTIAL
361: TLLETVPSMS YISMMAIFGF VAFFEVGPGP IPWFFVAELF SQGPRPAAMA VAGCSNWTAN
421: FIIGMGFQYV ANLCGPYVFL IFAALLLFFL IFTFFRVPET RGKTFDQISA TFHGHPQNMM
481: DMDLGLDQGK HSTELDYLGS DGTEN