2.A.1.1.160
L-Arabinose high specificity and affinity uptake transporter of 514 aas and 12 TMSs in a 6 + 6 TMS arrangement. The system has low affinity for D-xylose and almost no affinity for D-glucose. It has use for bioengineering purposes (Havukainen et al. 2021). Due to its high affinity for L-arabinose and low inhibition by D-glucose
or D-xylose, Trire2_104072 (AraE) could serve as a good candidate for
improving existing pentose-utilizing yeast strains.
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| Accession Number: | ETS04871.1 |
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| Protein Name: | ETS04871.1 putative xylose permease [Trichoderma reesei RUT C-30] |
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| Length: | 515 |
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| Molecular Weight: | |
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| Species: | Trichoderma reesei RUT C-30 [1344414] |
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| Number of TMSs: | 12 |
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| Substrate |
L-arabinopyranose |
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1: MYRIWNIYVL AAFGTIGGMI FGFEISSMSA WIGSEQYLEY FNHPDSTEQG GITAAMSAGS
61: LVGSLLAGWL ADRLGRRLAI QIASVDWIVG AVLQCSSQNV AHLVVGRIVS GLAIGITSSQ
121: CIVYLSELAP SRIRGRVVGI QQWSIDWGIL IMYLISYGCS VSIHRPAAFR IAWGLQAVPG
181: AVLFFSLFFF PESPRWLATK DRWEECHEVL ANLHAKGDRN NIEVLAELEE VREAARIAAE
241: SKEIGYLGLF APKMWKRTLV GVSAQIWQQL LGGNVMLYYL VYIFNMAGMS GNTALTSSII
301: QYVIFLVTTG GVLFVVDRIG RRWLLIVGAI ICGVIHFIVG AVMAVYGHHV DSVDGNDILR
361: WQIGGPPAKA IIALCYIFVG VYGVTWAPGA WIYCGEVFPL KYRAKGVGLA AAGNWAFNLA
421: LAFFVPPAFT NIQWKAYMIF GTFCIAMVFH IYFMYPETVK KSLEEIDVLF EGDIPAWRSA
481: SAVSTFDEKV ARAKEAGGLE EFSKQADIKH EEKV