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2.A.1.1.37 The glucose/fructose facilitator, Glut7 (SLC2A7) (a single mutation, I314V, results in loss of fructose transport but retention of glucose transport (Manolescu et al., 2005)
Accession Number:	Q6PXP3
Protein Name:	Glut7
Length:	512
Molecular Weight:	55728.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate

Structure:
RefSeq:	NP_997303.2
Entrez Gene ID:	155184
Pfam:	PF00083
OMIM:	610371 gene
KEGG:	hsa:155184 hsa:155184
Gene Ontology GO:0016021 C:integral to membrane GO:0005353 F:fructose transmembrane transporter activity GO:0008643 P:carbohydrate transport GO:0055085 P:transmembrane transport GO:0005886 C:plasma membrane GO:0022891 F:substrate-specific transmembrane transporter activity
References (4) [1] “Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine.” Li Q.et.al. 15033637 [2] “The DNA sequence and biological annotation of human chromosome 1.” Gregory S.G.et.al. 16710414 [3] “Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine.” Li Q.et.al. 15033637 [4] “The DNA sequence and biological annotation of human chromosome 1.” Gregory S.G.et.al. 16710414
1YG7

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MENKEAGTPP PIPSREGRLQ PTLLLATLSA AFGSAFQYGY NLSVVNTPHK VFKSFYNETY 
61:	FERHATFMDG KLMLLLWSCT VSMFPLGGLL GSLLVGLLVD SCGRKGTLLI NNIFAIIPAI 
121:	LMGVSKVAKA FELIVFSRVV LGVCAGISYS ALPMYLGELA PKNLRGMVGT MTEVFVIVGV 
181:	FLAQIFSLQA ILGNPAGWPV LLALTGVPAL LQLLTLPFFP ESPRYSLIQK GDEATARQAL 
241:	RRLRGHTDME AELEDMRAEA RAERAEGHLS VLHLCALRSL RWQLLSIIVL MAGQQLSGIN 
301:	AINYYADTIY TSAGVEAAHS QYVTVGSGVV NIVMTITSAV LVERLGRRHL LLAGYGICGS 
361:	ACLVLTVVLL FQNRVPELSY LGIICVFAYI AGHSIGPSPV PSVVRTEIFL QSSRRAAFMV 
421:	DGAVHWLTNF IIGFLFPSIQ EAIGAYSFII FAGICLLTAI YIYVVIPETK GKTFVEINRI 
481:	FAKRNRVKLP EEKEETIDAG PPTASPAKET SF

2.A.1.1.37
The glucose/fructose facilitator, Glut7 (SLC2A7) (a single mutation, I314V, results in loss of fructose transport but retention of glucose transport (Manolescu et al., 2005)

Cross database links:

Gene Ontology

References (4)

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2.A.1.1.37The glucose/fructose facilitator, Glut7 (SLC2A7) (a single mutation, I314V, results in loss of fructose transport but retention of glucose transport (Manolescu et al., 2005)

Cross database links:

Gene Ontology

References (4)

External Searches:

Analyze:

2.A.1.1.37
The glucose/fructose facilitator, Glut7 (SLC2A7) (a single mutation, I314V, results in loss of fructose transport but retention of glucose transport (Manolescu et al., 2005)