2.A.1.13.22
SLC16 Family protein of 771 aas and 12 TMSs, GEM-1. GEM-1 acts in parallel to the GON-2
channel (TC# 1.A.4.5.10) to promote cation uptake within the developing gonad (Kemp et al. 2009).
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| Accession Number: | Q18712 |
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| Protein Name: | C49F8.2 |
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| Length: | 771 |
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| Molecular Weight: | 85557.00 |
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| Species: | Caenorhabditis elegans [6239] |
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| Number of TMSs: | 12 |
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| Substrate |
cation |
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1: MTARRRPSMR TRMKAEDVSC WVEHNQQPFS PSDEPRVRFE APAPVSARSD DSDAESVESL
61: TERPVYKDGG YGWLVVLASF LMHAVCDGAS FCFGIVFVKI QEHFQCGRFV SMITASMFLS
121: LPLIMSPVAG IVSDILGCRM SIIIGASICT VSCIIAMFCS HIFFFMISFG LGCGVGMSFI
181: YNAAIVIVTY YFEKRRGLAT SFAVSGTGVG TVIYPILLNL SMIYLASFVS DIRIILIFFA
241: VMYFVIAVIG FFIKDVEWES DKTDFKLRKF QKYIAKMDDE KENNTNPTDA FMRHAISLPN
301: LNILNNHSGS IQSICDAAKA ERKSDKPTRS KSVALFDNKH QMSSIPEYSM LNTNLANLEH
361: LDLELANSPC TTVRAQRRRV ISKVSMSVDQ INELEDEAFH INLFQSSTES ESDDESSSDD
421: SEMSNDGDSS SSELSEKNLD EPTTKLINKN LENVAFRATS SVPNSARMNR NSVAAGTSNM
481: FGGRVIASNA IQSRHATNLI AMGKIPSAPM LVARKNRKSM IGKPIQGFYK KWLETEKPIY
541: QEVIHCRAYI YLALSVLCLY FILDVPYVCF YEYSIDTLKM EESEANYIYY SIGISNFISV
601: LLFGTLADWT RKHITTIYAS SMVGVGITIM FSTRINSLVE LVIVGVCFGV TITSNYVLQS
661: ILVTICFEDV NLFQVAYSLI AMIEGVASLI GPPIFALVRE ATGGYTVVFF ISGIFALASG
721: FFGFMFSYEM NKRNTGDKDS IESGKPTELT NGNNRQTSTG SGAEQETLLD V