2.A.1.13.25
Thyroid hormones (TH) transporter, MCT8 of 526 aas and 12 TMSs (Zada et al. 2017). The mechanisms underlying MCT8-deficient brain development in various animal models including zebra fish and humans has been reviewed (Vancamp and Darras 2017).
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| Accession Number: | L7T0T8 |
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| Protein Name: | Monocarboxylate transporter 8 |
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| Length: | 526 |
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| Molecular Weight: | 57120.00 |
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| Species: | Danio rerio (Zebrafish) [7955] |
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| Number of TMSs: | 12 |
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| Substrate |
thyroid hormone |
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1: MHSESDDNTA GGTPGSEDPQ AEESSSPAEE FEEQERKLAP EDSTVQLIHT GCTDKRPATP
61: PGAHPGQGFV PPEGGFGWVV VFAATWCNGS IFGIQNSFGI LHMMLVKHHE KQPDQASQFK
121: VAWVGALAMG MIFFCSPVVS MFTDHFGCRK TAVCGAFVAF IGLLTSSFAT TLGLWYFTYG
181: ILFGCGSSFA FQPSLVILGR YFRQRLGLAN GVVTAGSSLF SMGLPVLLKK VVEPLGLPRT
241: FQILSIFMLV QALLALAFKP LLPSGMCPMP GMALDGGPST PESASRWQKG LAKVRRYFNV
301: RVFSILTYRI WAFGVATAVL GYFVPYVHLL NFVKEQFGDT QREWLLLVCI GASSGVGRLL
361: FGKIGDLIPG VKKIYMQVAS FILLGVMSMM IPQCAVFEGL VVVFVLMGLC DGCFITIMAP
421: IAFELVGPMQ ASQAIGYLLG LMAIPMTAGP PIAGLLHDHF GNYHVAFYLA GVPPIVGGIV
481: MFFVPLVHQR MQKRRKETDD PSMDKMLKNC SNGDMLPGYT DMETHI