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| Accession Number: | Q14916 |
| Protein Name: | Sodium-dependent phosphate transport protein 1 |
| Length: | 467 |
| Molecular Weight: | 51132.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), phosphate(3-), 7,9-dihydro-1H-purine-2,6,8(3H)-trione |
Cross database links:
| Entrez Gene ID: | 6568 |
|---|---|
| Pfam: | PF07690 |
| KEGG: | hsa:6568 hsa:6568 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0005624
C:membrane fraction
GO:0015321
F:sodium-dependent phosphate transmembrane transporter activity
GO:0015293
F:symporter activity
GO:0006814
P:sodium ion transport
GO:0046415
P:urate metabolic process
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References (14)[1] “Molecular cloning of the cDNA encoding a human renal sodium phosphate transport protein and its assignment to chromosome 6p21.3-p23.” Chong S.S.et.al. 8288239 [2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [3] “The DNA sequence and analysis of human chromosome 6.” Mungall A.J.et.al. 14574404 [4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [5] “Murine and human type I Na-phosphate cotransporter genes: structure and promoter activity.” Soumounou Y.et.al. 11704559 [6] “Characterization of the 5' flanking region of the human NPT-1 Na+/phosphate cotransporter gene.” Taketani Y.et.al. 9545579 [7] “Cloning and functional expression of a Na(+)-dependent phosphate co-transporter from human kidney: cDNA cloning and functional expression.” Miyamoto K.et.al. 7826357 [8] “Molecular cloning of the cDNA encoding a human renal sodium phosphate transport protein and its assignment to chromosome 6p21.3-p23.” Chong S.S.et.al. 8288239 [9] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [10] “The DNA sequence and analysis of human chromosome 6.” Mungall A.J.et.al. 14574404 [11] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [12] “Murine and human type I Na-phosphate cotransporter genes: structure and promoter activity.” Soumounou Y.et.al. 11704559 [13] “Characterization of the 5' flanking region of the human NPT-1 Na+/phosphate cotransporter gene.” Taketani Y.et.al. 9545579 [14] “Cloning and functional expression of a Na(+)-dependent phosphate co-transporter from human kidney: cDNA cloning and functional expression.” Miyamoto K.et.al. 7826357
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MQMDNRLPPK KVPGFCSFRY GLSFLVHCCN VIITAQRACL NLTMVVMVNS TDPHGLPNTS 61: TKKLLDNIKN PMYNWSPDIQ GIILSSTSYG VIIIQVPVGY FSGIYSTKKM IGFALCLSSV 121: LSLLIPPAAG IGVAWVVVCR AVQGAAQGIV ATAQFEIYVK WAPPLERGRL TSMSTSGFLL 181: GPFIVLLVTG VICESLGWPM VFYIFGACGC AVCLLWFVLF YDDPKDHPCI SISEKEYITS 241: SLVQQVSSSR QSLPIKAILK SLPVWAISTG SFTFFWSHNI MTLYTPMFIN SMLHVNIKEN 301: GFLSSLPYLF AWICGNLAGQ LSDFFLTRNI LSVIAVRKLF TAAGFLLPAI FGVCLPYLSS 361: TFYSIVIFLI LAGATGSFCL GGVFINGLDI APRYFGFIKA CSTLTGMIGG LIASTLTGLI 421: LKQDPESAWF KTFILMAAIN VTGLIFYLIV ATAEIQDWAK EKQHTRL